MRPL9 Antibody (PACO31876)
- SKU:
- PACO31876
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- WB
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
MRPL9 Antibody (PACO31876)
The MRPL9 Monoclonal Antibody (PAC031876) is a key tool for researchers studying mitochondrial ribosomal protein L9 (MRPL9), a vital component of the mitochondrial ribosome. This antibody, generated from hybridoma cells, demonstrates high specificity and sensitivity for detecting MRPL9 in human samples, making it ideal for a variety of research applications, including Western blot and immunofluorescence.MRPL9 is essential for protein synthesis within the mitochondria, playing a crucial role in maintaining mitochondrial function and cellular energy production. Dysregulation of MRPL9 has been linked to various diseases, including neurodegenerative disorders and metabolic conditions.
Studying the expression and function of MRPL9 is therefore fundamental for understanding mitochondrial biology and developing targeted therapies for related diseases.By utilizing the MRPL9 Monoclonal Antibody, researchers can accurately detect and analyze MRPL9 in different cell types and tissues, advancing our knowledge of mitochondrial ribosome function and its implications in health and disease. This antibody is a valuable tool for investigations in fields such as molecular biology, biochemistry, and mitochondrial biology.
| Antibody Name: | MRPL9 Antibody (PACO31876) |
| Antibody SKU: | PACO31876 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB |
| Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:500-1:5000 |
| Species Reactivity: | Human |
| Immunogen: | Recombinant Human 39S ribosomal protein L9, mitochondrial protein (60-267AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Western blot All lanes: MRPL9 antibody at 2µg/ml Lane 1: EC109 whole cell lysate Lane 2: 293T whole cell lysate Secondary Goat polyclonal to rabbit IgG at 1/15000 dilution Predicted band size: 31 kDa Observed band size: 31 kDa . |
| Synonyms: | 39S ribosomal protein L9, mitochondrial (L9mt) (MRP-L9) (Mitochondrial large ribosomal subunit protein bL9m), MRPL9 |
| UniProt Protein Function: | MRPL9: a mitochondrial ribosomal protein encoded by a nuclear gene that helps in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. A pseudogene corresponding to this gene is found at 8q21.11. [provided by RefSeq, Jul 2008] |
| UniProt Protein Details: | Protein type:Ribosomal; Mitochondrial; Translation Chromosomal Location of Human Ortholog: 1q21 Cellular Component: mitochondrial inner membrane; mitochondrion Molecular Function:protein binding Biological Process: translation |
| NCBI Summary: | This is a nuclear gene encoding a protein component of the 39S subunit of the mitochondrial ribosome. Alternative splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 8. [provided by RefSeq, Jul 2014] |
| UniProt Code: | Q9BYD2 |
| NCBI GenInfo Identifier: | 209572671 |
| NCBI Gene ID: | 65005 |
| NCBI Accession: | Q9BYD2.2 |
| UniProt Secondary Accession: | Q9BYD2,Q5SZR2, Q9BSW8, B2RD99, |
| UniProt Related Accession: | Q9BYD2 |
| Molecular Weight: | 30,243 Da |
| NCBI Full Name: | 39S ribosomal protein L9, mitochondrial |
| NCBI Synonym Full Names: | mitochondrial ribosomal protein L9 |
| NCBI Official Symbol: | MRPL9 |
| NCBI Official Synonym Symbols: | L9mt |
| NCBI Protein Information: | 39S ribosomal protein L9, mitochondrial |
| UniProt Protein Name: | 39S ribosomal protein L9, mitochondrial |
| Protein Family: | 39S ribosomal protein |
| UniProt Gene Name: | MRPL9 |
| UniProt Entry Name: | RM09_HUMAN |
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