MRPL9 Antibody (PACO22090)
- SKU:
- PACO22090
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- WB
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
MRPL9 Antibody (PACO22090)
The MRPL9 Antibody (PACO22090) is a polyclonal antibody designed for research involving the MRPL9 protein, which plays a key role in cellular function. The antibody, raised in rabbits, is highly reactive with human samples and is validated for use in various applications including Western blot and immunofluorescence. It specifically binds to the MRPL9 protein, allowing for detection and analysis in different cell types.MRPL9 is a mitochondrial ribosomal protein that is essential for protein synthesis within the mitochondria. It is involved in the assembly of the mitochondrial ribosome and plays a crucial role in maintaining mitochondrial function.
Research on MRPL9 is important for understanding mitochondrial dysfunction, which is implicated in various diseases including cancer, neurodegenerative disorders, and metabolic disorders.The MRPL9 Antibody (PACO22090) is a valuable tool for investigators studying mitochondrial biology and its impact on health and disease. By targeting the MRPL9 protein, researchers can gain insights into the mechanisms underlying mitochondrial dysfunction and potentially develop targeted therapies for related conditions.
| Antibody Name: | MRPL9 Antibody (PACO22090) |
| Antibody SKU: | PACO22090 |
| Size: | 100ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB |
| Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:500-1:3000 |
| Species Reactivity: | Human, Mouse, Rat |
| Immunogen: | Synthesized peptide derived from internal of human MRPL9. |
| Form: | Liquid |
| Storage Buffer: | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Purification Method: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Western blot analysis of extracts from COLO cells, using MRPL9 antibody. |
| Background: | This is a nuclear gene encoding a protein component of the 39S subunit of the mitochondrial ribosome. Alternative splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 8. |
| Synonyms: | 39S ribosomal L9; mitochondrial; L9mt; mitochondrial ribosomal L9; MRP-L9 |
| UniProt Protein Function: | MRPL9: a mitochondrial ribosomal protein encoded by a nuclear gene that helps in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. A pseudogene corresponding to this gene is found at 8q21.11. [provided by RefSeq, Jul 2008] |
| UniProt Protein Details: | Protein type:Ribosomal; Mitochondrial; Translation Chromosomal Location of Human Ortholog: 1q21 Cellular Component: mitochondrial inner membrane; mitochondrion Molecular Function:protein binding Biological Process: translation |
| NCBI Summary: | This is a nuclear gene encoding a protein component of the 39S subunit of the mitochondrial ribosome. Alternative splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 8. [provided by RefSeq, Jul 2014] |
| UniProt Code: | Q9BYD2 |
| NCBI GenInfo Identifier: | 209572671 |
| NCBI Gene ID: | 65005 |
| NCBI Accession: | Q9BYD2.2 |
| UniProt Secondary Accession: | Q9BYD2,Q5SZR2, Q9BSW8, B2RD99, |
| UniProt Related Accession: | Q9BYD2 |
| Molecular Weight: | 30,243 Da |
| NCBI Full Name: | 39S ribosomal protein L9, mitochondrial |
| NCBI Synonym Full Names: | mitochondrial ribosomal protein L9 |
| NCBI Official Symbol: | MRPL9Â Â |
| NCBI Official Synonym Symbols: | L9mt  |
| NCBI Protein Information: | 39S ribosomal protein L9, mitochondrial |
| UniProt Protein Name: | 39S ribosomal protein L9, mitochondrial |
| Protein Family: | 39S ribosomal protein |
| UniProt Gene Name: | MRPL9Â Â |
| UniProt Entry Name: | RM09_HUMAN |
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