The MRPL55 Polyclonal Antibody (CAB18242) is a valuable tool for researchers studying mitochondrial ribosomal proteins. This antibody, raised in rabbits, is highly specific and reactive with human samples, making it ideal for use in Western blot applications. It binds specifically to the MRPL55 protein, allowing for easy detection and analysis in a variety of cell types.MRPL55 is a part of the mitochondrial ribosome, which is responsible for protein synthesis within the mitochondria. The function of MRPL55 is essential for proper mitochondrial function and overall cellular health.
Research involving MRPL55 is important for understanding the role of mitochondrial ribosomal proteins in various diseases, including cancer, neurodegenerative disorders, and metabolic diseases.By utilizing the MRPL55 Polyclonal Antibody, researchers can gain valuable insights into the function and regulation of MRPL55, ultimately furthering our understanding of mitochondrial protein synthesis and its implications in disease. This antibody is a reliable tool for those studying mitochondrial biology, protein synthesis, and related pathways.
Product Name:
MRPL55 Rabbit Polyclonal Antibody
SKU:
CAB18242
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-128 of human MRPL55 (NP_001308213.1).
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. Multiple transcript variants encoding two different isoforms were identified through sequence analysis.
Purification Method:
Affinity purification
Gene ID:
128308
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from MCF7 cells, using MRPL55 Rabbit pAb (CAB18242) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.
