The MRPL51 Polyclonal Antibody (CAB15838) is a valuable tool for researchers studying mitochondrial ribosomal proteins. This antibody, generated in rabbits, exhibits high reactivity with human samples and is validated for use in Western blot applications. By binding specifically to the MRPL51 protein, this antibody enables accurate detection and analysis in a variety of cell types.MRPL51 is a crucial component of the mitochondrial ribosome, playing a key role in protein synthesis within the mitochondria.
Research on MRPL51 is essential for understanding mitochondrial function and its implications in various diseases, including metabolic disorders and cancer. The MRPL51 Polyclonal Antibody opens up new possibilities for investigating the role of this protein in cellular processes, making it an excellent tool for studies in molecular biology and biochemistry.
Product Name:
MRPL51 Rabbit Polyclonal Antibody
SKU:
CAB15838
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-128 of human MRPL51 (NP_057581.2).
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. Pseudogenes corresponding to this gene are found on chromosomes 4p and 21q.
Purification Method:
Affinity purification
Gene ID:
51258
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using MRPL51 Rabbit pAb (CAB15838) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
