MRPL50 Antibody (PACO38798)
- SKU:
- PACO38798
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- IHC
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
MRPL50 Antibody (PACO38798)
The MRPL50 Polyclonal Antibody (PACO38798) is a valuable tool for researchers studying MRPL50, a mitochondrial ribosomal protein involved in protein synthesis within the mitochondria. This antibody, produced in rabbits, has been validated for use in Western blot applications and is highly reactive with human samples.MRPL50 plays a crucial role in maintaining mitochondrial function and has been implicated in various diseases, including cancer and neurodegenerative disorders.
By targeting MRPL50 with this antibody, researchers can investigate its role in mitochondrial protein synthesis and potentially uncover new insights into mitochondrial dysfunction and its connection to disease pathology.In summary, the MRPL50 Polyclonal Antibody (PACO38798) is a reliable antibody for studying the function of MRPL50 in mitochondrial protein synthesis, making it a valuable tool for research in areas such as cancer biology and neurodegenerative diseases.
| Antibody Name: | MRPL50 Antibody (PACO38798) |
| Antibody SKU: | PACO38798 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, IHC |
| Recommended Dilutions: | ELISA:1:2000-1:10000, IHC:1:20-1:200 |
| Species Reactivity: | Human |
| Immunogen: | Recombinant Human 39S ribosomal protein L50, mitochondrial protein (1-158AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Immunohistochemistry of paraffin-embedded human lung tissue using PACO38798 at dilution of 1:100. |
 | Immunohistochemistry of paraffin-embedded human ovarian cancer using PACO38798 at dilution of 1:100. |
| Background: | mitochondrial inner membrane, mitochondrial translation, mitochondrial translational elongation, mitochondrial translational initiation, mitochondrial translational termination, organelle organization |
| Synonyms: | 39S ribosomal protein L50, mitochondrial (L50mt) (MRP-L50) (Mitochondrial large ribosomal subunit protein mL50), MRPL50 |
| UniProt Protein Function: | MRPL50: 2 isoforms of the human protein are produced by alternative splicingChromosomal Location of Human Ortholog: 9q31.1Cellular Component: mitochondrial inner membrane |
| UniProt Protein Details: | |
| NCBI Summary: | Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a putative 39S subunit protein and belongs to the L47P ribosomal protein family. Pseudogenes corresponding to this gene are found on chromosomes 2p, 2q, 5p, and 10q. [provided by RefSeq, Jul 2008] |
| UniProt Code: | Q8N5N7 |
| NCBI GenInfo Identifier: | 118573685 |
| NCBI Gene ID: | 54534 |
| NCBI Accession: | Q8N5N7.2 |
| UniProt Secondary Accession: | Q8N5N7,Q5T7E0, Q9NX15, B7Z358 |
| UniProt Related Accession: | Q8N5N7 |
| Molecular Weight: | 15,524 Da |
| NCBI Full Name: | 39S ribosomal protein L50, mitochondrial |
| NCBI Synonym Full Names: | mitochondrial ribosomal protein L50 |
| NCBI Official Symbol: | MRPL50Â Â |
| NCBI Official Synonym Symbols: | MRP-L50Â Â |
| NCBI Protein Information: | 39S ribosomal protein L50, mitochondrial |
| UniProt Protein Name: | 39S ribosomal protein L50, mitochondrial |
| UniProt Synonym Protein Names: | |
| Protein Family: | 39S ribosomal protein |
| UniProt Gene Name: | MRPL50Â Â |
| UniProt Entry Name: | RM50_HUMAN |
| Antibodies |
| MRPL50 Antibody (PACO01103) |
| Secondary Antibody |
| Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
| Recommended Products |
| Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
| Anti-HRP-conjugated Beta Actin Antibody (CABC028) |
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