The MRPL48 Polyclonal Antibody (CAB18188) is a valuable tool for researchers studying MRPL48, a mitochondrial ribosomal protein essential for protein synthesis within the mitochondria. This antibody, generated in rabbits, exhibits high reactivity with human samples and has been validated for use in various applications, including Western blotting.MRPL48 plays a crucial role in the biogenesis of mitochondrial ribosomes, which are responsible for translating mitochondrial DNA into functional proteins essential for cellular respiration. Dysregulation of MRPL48 has been linked to mitochondrial dysfunction, leading to various human diseases, including metabolic disorders and neurodegenerative diseases.
By using the MRPL48 Polyclonal Antibody, researchers can explore the expression levels and localization of MRPL48 in different cell types and tissues, providing valuable insights into its role in mitochondrial protein synthesis and function. This antibody is an invaluable tool for studies focusing on mitochondrial biology, bioenergetics, and the molecular mechanisms underlying mitochondrial-related diseases.
Product Name:
Mrpl48 Rabbit Polyclonal Antibody
SKU:
CAB18188
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 28-211 of mouse Mrpl48 (NP_942128.2).
Located in mitochondrion. Is expressed in several structures, including early conceptus; gonad; heart; liver; and metanephros. Orthologous to human MRPL48 (mitochondrial ribosomal protein L48).
Purification Method:
Affinity purification
Gene ID:
52443
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using Mrpl48 Rabbit pAb (CAB18188) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 180s.
