MRPL43 Rabbit Polyclonal Antibody (CAB17793)
- SKU:
- CAB17793
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Description
Product Name: | MRPL43 Rabbit Polyclonal Antibody |
SKU: | CAB17793 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 80-155 of human MRPL43 (NP_789762.1). |
Sequence: | LNGA VREE SIHC KSVE EIST LVQK LADQ SGLD VIRI RKPF HTDN PSIQ GQWH PFTN KPTT FRGL RPRE VQDP APAQ |
Tested Applications: | WB IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IF/ICC,1:50 - 1:200 |
Synonyms: | L43mt; MRP-L43; bMRP36a; MRPL43 |
Positive Sample: | A-549,PC-3,293T |
Conjugate: | Unconjugated |
Cellular Localization: | mitochondrial inner membrane, mitochondrial ribosome, mitochondrion |
Calculated MW: | 23kDa |
Observed MW: | 23kDa |
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. This gene and the gene for a semaphorin class 4 protein (SEMA4G) overlap at map location 10q24.31 and are transcribed in opposite directions. Sequence analysis identified multiple transcript variants encoding at least four different protein isoforms.
Purification Method: | Affinity purification |
Gene ID: | 84545 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |