The MRPL41 Polyclonal Antibody (CAB17760) is a valuable tool for researchers studying mitochondrial ribosomal protein L41 (MRPL41), a key component of the mitochondrial ribosome involved in protein synthesis within the mitochondria. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By specifically binding to the MRPL41 protein, this antibody enables precise detection and analysis in a variety of cell types, making it well-suited for investigations in the fields of biochemistry and molecular biology.MRPL41 plays a crucial role in the maintenance of mitochondrial function and is essential for proper cellular metabolism.
Dysfunction in mitochondrial ribosomal proteins, such as MRPL41, has been linked to a variety of diseases, including metabolic disorders and neurodegenerative conditions. As such, understanding the function and regulation of MRPL41 is vital for unlocking insights into these health conditions and developing potential therapeutic interventions. Researchers can rely on the MRPL41 Polyclonal Antibody (CAB17760) to support their investigations into the role of MRPL41 in health and disease.
Product Name:
MRPL41 Rabbit Polyclonal Antibody
SKU:
CAB17760
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-137 of human MRPL41 (NP_115866.1).
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein that belongs to the YmL27 ribosomal protein family.
Purification Method:
Affinity purification
Gene ID:
64975
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using MRPL41 Rabbit pAb (CAB17760) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 90s.
