MRPL40 Rabbit Polyclonal Antibody (CAB18191)
- SKU:
- CAB18191
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Description
Product Name: | MRPL40 Rabbit Polyclonal Antibody |
SKU: | CAB18191 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 45-206 of human MRPL40 (NP_003767.2). |
Sequence: | MRSE PLRK KKKV DPKK DQEA KERL KRKI RKLE KATQ ELIP IEDF ITPL KFLD KARE RPQV ELTF EETE RRAL LLKK WSLY KQQE RKME RDTI RAML EAQQ EALE ELQL ESPK LHAE AIKR DPNL FPFE KEGP HYTP PIPN YQPP EGRY NDIT KVYT QVEF KR |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | URIM; L40mt; NLVCF; MRPL22; MRP-L22; MRP-L40; MRPL40 |
Positive Sample: | A-549,U2OS,BxPC-3 |
Cellular Localization: | mitochondrial inner membrane, mitochondrial ribosome, mitochondrion, nucleolus, nucleus |
Calculated MW: | 24kDa |
Observed MW: | 24kDa |
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. Deletions in this gene may contribute to the etiology of velo-cardio-facial syndrome and DiGeorge syndrome.
Purification Method: | Affinity purification |
Gene ID: | 64976 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |