The MRPL38 Polyclonal Antibody (CAB18239) is a valuable tool for researchers studying MRPL38, a protein involved in mitochondrial protein synthesis. This rabbit-raised antibody is highly specific and reactive with human samples, making it suitable for Western blot applications. By binding to the MRPL38 protein, this antibody enables accurate detection and analysis in a variety of cell types, making it an excellent choice for studies in mitochondrial biology and biochemistry.MRPL38 plays a crucial role in the ribosomal machinery of the mitochondria, making it essential for proper protein synthesis within this organelle.
Understanding the function and regulation of MRPL38 is important for gaining insights into mitochondrial function and dysfunction, which have implications for various diseases including metabolic disorders, neurodegenerative diseases, and cancer. By using the MRPL38 Polyclonal Antibody, researchers can uncover new findings and advance our knowledge in the field of mitochondrial biology.
Product Name:
MRPL38 Rabbit Polyclonal Antibody
SKU:
CAB18239
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 35-380 of human MRPL38 (NP_115867.2).
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein.
Purification Method:
Affinity purification
Gene ID:
64978
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using MRPL38 Rabbit pAb (CAB18239) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 5s.
