The MRPL36 Monoclonal Antibody (PAC010586) is a powerful tool for researchers studying mitochondrial ribosomal protein L36 (MRPL36), an essential component of the mitochondrial ribosome. This antibody, produced using cutting-edge technology, specifically targets MRPL36 and is highly specific in detecting this protein in various cell types.MRPL36 is a key player in protein synthesis within the mitochondria, making it crucial for proper cell function and energy production. Dysregulation of MRPL36 has been implicated in diseases such as mitochondrial disorders and cancer, highlighting its importance in cellular health.
This antibody is validated for use in a variety of applications, including Western blot, immunofluorescence, and immunohistochemistry, providing researchers with flexibility in their experimental design. By utilizing the MRPL36 Monoclonal Antibody, scientists can gain valuable insights into the role of MRPL36 in mitochondrial function and its potential implications in disease pathology.
mitochondrial ribosomal protein L36;MRPL36;BRIP1;L36mt;MGC104245;MRP-L36;PRPL36;RPMJ ;
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NCBI Summary:
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. A pseudogene corresponding to this gene is found on chromosome 2p. [provided by RefSeq, Jul 2008]
