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MRPL19 Antibody (PACO28342)

SKU:
PACO28342
Product Type:
Antibody
Reactivity:
Human
Mouse
Host Species:
Rabbit
Isotype:
IgG
Applications:
ELISA
WB
IHC
IF
Antibody Type:
Polyclonal Antibody
Conjugation:
Unconjugated
  • MRPL19 Antibody PACO28342
  • MRPL19 Antibody PACO28342
  • MRPL19 Antibody PACO28342
€339

Description

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MRPL19 Antibody (PACO28342)

The MRPL19 Polyclonal Antibody (PAC028342) is a valuable tool for researchers studying mitochondrial ribosomal protein L19 (MRPL19), a key component of the mitochondrial ribosome involved in protein synthesis within the mitochondria. This antibody, produced in rabbits, exhibits strong reactivity with human samples and is validated for use in Western blot applications. By binding specifically to MRPL19, researchers can accurately detect and analyze this protein in a variety of cell types, making it an excellent choice for studies in molecular biology and mitochondrial research.

MRPL19 is essential for proper mitochondrial function and plays a vital role in the synthesis of proteins necessary for energy production within the cell. Dysregulation of MRPL19 has been linked to various mitochondrial disorders and diseases, making it a promising target for further investigation in the field of mitochondrial biology and related pathologies. By studying the function and expression of MRPL19, researchers can gain valuable insights into mitochondrial dysfunction and potentially develop new therapeutic strategies for mitochondrial-related diseases.

Antibody Name:MRPL19 Antibody (PACO28342)
Antibody SKU:PACO28342
Size:50ug
Host Species:Rabbit
Tested Applications:ELISA, WB, IHC, IF
Recommended Dilutions:ELISA:1:2000-1:10000, WB:1:500-1:5000, IHC:1:20-1:200, IF:1:50-1:200
Species Reactivity:Human, Mouse
Immunogen:Recombinant Human 39S ribosomal protein L19, mitochondrial protein (1-292AA)
Form:Liquid
Storage Buffer:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Purification Method:>95%, Protein G purified
Clonality:Polyclonal
Isotype:IgG
Conjugate:Non-conjugated
Product ImageWestern blot
All lanes: MRPL19 antibody at 2µg/ml
Lane 1: MCF-7 whole cell lysate
Lane 2: Mouse liver tissue
Secondary
Goat polyclonal to rabbit IgG at 1/10000 dilution
Predicted band size: 34 kDa
Observed band size: 34 kDa
.
Product ImageImmunofluorescent analysis of Hela cells using PACO28342 at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
Product ImageImmunohistochemistry of paraffin-embedded human placenta tissue using PACO28342 at dilution of 1:100.
Synonyms:39S ribosomal protein L19, mitochondrial (L19mt) (MRP-L19) (39S ribosomal protein L15, mitochondrial) (L15mt) (MRP-L15) (Mitochondrial large ribosomal subunit protein bL19m), MRPL19, KIAA0104 MRPL15
UniProt Protein Function:MRPL19: a mitochondrial ribosomal protein encoded by a nuclear gene that helps in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. [provided by RefSeq, Jul 2008]Protein type: Translation; Ribosomal; MitochondrialChromosomal Location of Human Ortholog: 2p11.1-q11.2Cellular Component: mitochondrial inner membrane; mitochondrial large ribosomal subunit; nuclear membrane; nucleusMolecular Function: structural constituent of ribosome
UniProt Protein Details:
NCBI Summary:Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. [provided by RefSeq, Jul 2008]
UniProt Code:P49406
NCBI GenInfo Identifier:92090636
NCBI Gene ID:9801
NCBI Accession:P49406.2
UniProt Secondary Accession:P49406,Q53TX9, Q96Q52
UniProt Related Accession:P49406
Molecular Weight:33,535 Da
NCBI Full Name:39S ribosomal protein L19, mitochondrial
NCBI Synonym Full Names:mitochondrial ribosomal protein L19
NCBI Official Symbol:MRPL19  
NCBI Official Synonym Symbols:RLX1; L19mt; MRPL15; RPML15; MRP-L15; MRP-L19  
NCBI Protein Information:39S ribosomal protein L19, mitochondrial
UniProt Protein Name:39S ribosomal protein L19, mitochondrial
UniProt Synonym Protein Names:39S ribosomal protein L15, mitochondrial; L15mt; MRP-L15
Protein Family:39S ribosomal protein
UniProt Gene Name:MRPL19  
UniProt Entry Name:RM19_HUMAN
Antibodies
MRPL19 Antibody (PACO10577)
Secondary Antibody
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014)
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