The MRPL18 Polyclonal Antibody (CAB18186) is a valuable tool for researchers studying MRPL18, a mitochondrial ribosomal protein essential for protein synthesis within the mitochondria. This antibody, generated in rabbits, is highly specific and reactive with human samples, making it suitable for various research applications such as Western blotting and immunohistochemistry.MRPL18 plays a crucial role in the assembly of the mitochondrial ribosome and the translation of mitochondrial-encoded proteins, making it a key player in mitochondrial function and cellular energy production.
Dysregulation of MRPL18 has been linked to various diseases, including cancer and metabolic disorders, making it a potential therapeutic target for drug development.By using the MRPL18 Polyclonal Antibody, researchers can investigate the expression levels and localization of MRPL18 in different cell types and tissues, providing valuable insights into its function and potential role in disease pathogenesis. This antibody is a valuable asset for studies in mitochondrial biology, cancer research, and metabolic disorders.
Product Name:
Mrpl18 Rabbit Polyclonal Antibody
SKU:
CAB18186
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 42-180 of mouse Mrpl18 (NP_080586.1).
Predicted to enable 5S rRNA binding activity. Predicted to be involved in rRNA import into mitochondrion. Located in mitochondrion. Is expressed in several structures, including brain; connective tissue; early conceptus; genitourinary system; and gut. Orthologous to human MRPL18 (mitochondrial ribosomal protein L18).
Purification Method:
Affinity purification
Gene ID:
67681
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using Mrpl18 Rabbit pAb (CAB18186) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 180s.
