The MRPL18 Polyclonal Antibody (CAB16231) is a valuable tool for researchers studying MRPL18, a protein involved in mitochondrial ribosome assembly. This antibody, raised in rabbits, exhibits high reactivity with human samples and is validated for use in Western blot applications. By binding specifically to the MRPL18 protein, the antibody enables accurate detection and analysis in various cell types, making it ideal for studies in mitochondrial biology and disease research.MRPL18 is a crucial component of mitochondrial ribosomes responsible for synthesizing proteins essential for mitochondrial function. Dysregulation of MRPL18 has been linked to various mitochondrial disorders and diseases, highlighting its significance in cellular metabolism and energy production.
Understanding the role of MRPL18 in mitochondrial function is essential for advancing research and developing therapeutic strategies for mitochondrial-related disorders.Overall, the MRPL18 Polyclonal Antibody (CAB16231) provides researchers with a reliable tool for investigating the function and dysregulation of MRPL18 in various biological processes, ultimately contributing to advancements in mitochondrial research and potential therapeutic interventions.
Product Name:
MRPL18 Rabbit Polyclonal Antibody
SKU:
CAB16231
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-92 of human MRPL18 (NP_054880.2).
This nuclear gene encodes a protein component of the larger 39S subunit of mitochondrial ribosome. This protein may also aid in the import of nuclear-encoded 5S rRNA into mitochondria. Alternative splicing results in multiple transcript variants, most of which are not predicted to encode a protein. A pseudogene of this gene is found on chromosome 16.
Purification Method:
Affinity purification
Gene ID:
29074
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using MRPL18 Rabbit pAb (CAB16231) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 90s.
