The MRPL16 Polyclonal Antibody (PACO01093) is a valuable tool for researchers studying the MRPL16 protein, a key player in mitochondrial protein synthesis. This antibody, produced in rabbits, is specifically designed for use in Western blot applications and is highly reactive with samples from various species, including human, mouse, and rat.MRPL16 is a mitochondrial ribosomal protein involved in the translation of mitochondrial proteins essential for proper mitochondrial function. Dysregulation of MRPL16 has been linked to various diseases, including cancer, neurodegenerative disorders, and metabolic diseases.
By targeting MRPL16 with this antibody, researchers can study its expression and activity in different cell types, contributing to a better understanding of mitochondrial biology and its implications in disease pathology.With its high specificity and sensitivity, the MRPL16 Polyclonal Antibody is a valuable tool for researchers conducting studies in the fields of molecular biology, biochemistry, and mitochondrial research. Its versatility and reliability make it an essential component for investigating the role of MRPL16 in health and disease.
Antibody Name:
MRPL16 Antibody
Antibody SKU:
PACO01093
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, WB, IHC
Recommended Dilutions:
WB:1:500-1:2000, IHC:1:100-1:300
Species Reactivity:
Human
Immunogen:
synthesized peptide derived from the C-terminal region of human MRP-L16.
Form:
Liquid
Storage Buffer:
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification Method:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
Synonyms:
MRPL16; PNAS-111; 39S ribosomal protein L16; mitochondrial; L16mt; MRP-L16
UniProt Protein Function:
UniProt Protein Details:
NCBI Summary:
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. [provided by RefSeq, Jul 2008]
