UniProt Protein Function: | MRPL14: Forms part of 2 intersubunit bridges in the assembled ribosome. Upon binding to MALSU1 intersubunit bridge formation is blocked, preventing ribosome formation and repressing translation (Probable). Belongs to the ribosomal protein L14P family.Protein type: TranslationChromosomal Location of Human Ortholog: 6p21.3Cellular Component: mitochondrial inner membrane; ribosomeMolecular Function: structural constituent of ribosomeBiological Process: mitochondrial translation; organelle organization and biogenesis |
UniProt Protein Details: | |
NCBI Summary: | Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. A pseudogene corresponding to this gene is found at 17p13.3. [provided by RefSeq, Jul 2008] |
UniProt Code: | Q6P1L8 |
NCBI GenInfo Identifier: | 55769543 |
NCBI Gene ID: | 64928 |
NCBI Accession: | NP_115487.2 |
UniProt Secondary Accession: | Q6P1L8,Q96Q72, B2R575 |
UniProt Related Accession: | Q6P1L8 |
Molecular Weight: | 15,948 Da |
NCBI Full Name: | 39S ribosomal protein L14, mitochondrial |
NCBI Synonym Full Names: | mitochondrial ribosomal protein L14 |
NCBI Official Symbol: | MRPL14Â Â |
NCBI Official Synonym Symbols: | L14mt; L32mt; MRPL32; RMPL32; RPML32; MRP-L14; MRP-L32Â Â |
NCBI Protein Information: | 39S ribosomal protein L14, mitochondrial; 39S ribosomal protein L32, mitochondrial |
UniProt Protein Name: | 39S ribosomal protein L14, mitochondrial |
UniProt Synonym Protein Names: | 39S ribosomal protein L32, mitochondrial |
Protein Family: | 39S ribosomal protein |
UniProt Gene Name: | MRPL14Â Â |
UniProt Entry Name: | RM14_HUMAN |