RAE1 Rabbit Polyclonal Antibody (CAB6713)
- SKU:
- CAB6713
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Cycle
Frequently bought together:
Description
Product Name: | RAE1 Rabbit Polyclonal Antibody |
SKU: | CAB6713 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-368 of human RAE1 (NP_003601.1). |
Sequence: | MSLF GTTS GFGT SGTS MFGS ATTD NHNP MKDI EVTS SPDD SIGC LSFS PPTL PGNF LIAG SWAN DVRC WEVQ DSGQ TIPK AQQM HTGP VLDV CWSD DGSK VFTA SCDK TAKM WDLS SNQA IQIA QHDA PVKT IHWI KAPN YSCV MTGS WDKT LKFW DTRS SNPM MVLQ LPER CYCA DVIY PMAV VATA ERGL IVYQ LENQ PSEF RRIE SPLK HQHR CVAI FKDK QNKP TGFA LGSI EGRV AIHY INPP NPAK DNFT FKCH RSNG TNTS APQD IYAV NGIA FHPV HGTL ATVG SDGR FSFW DKDA RTKL KTSE QLDQ PISA CCFN HNGN IFAY ASSY DWSK GHEF YNPQ KKNY IFLR NAAE ELKP RNKK |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | Gle2; MIG14; MRNP41; Mnrp41; dJ481F12.3; dJ800J21.1; RAE1 |
Positive Sample: | Mouse brain,Mouse spleen,Mouse thymus,Rat brain |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm, Nucleus. |
Calculated MW: | 41kDa |
Observed MW: | 40kDa |
Mutations in the Schizosaccharomyces pombe Rae1 and Saccharomyces cerevisiae Gle2 genes have been shown to result in accumulation of poly(A)-containing mRNA in the nucleus, suggesting that the encoded proteins are involved in RNA export. The protein encoded by this gene is a homolog of yeast Rae1. It contains four WD40 motifs, and has been shown to localize to distinct foci in the nucleoplasm, to the nuclear rim, and to meshwork-like structures throughout the cytoplasm. This gene is thought to be involved in nucleocytoplasmic transport, and in directly or indirectly attaching cytoplasmic mRNPs to the cytoskeleton. Alternatively spliced transcript variants encoding the same protein have been found for this gene.
Purification Method: | Affinity purification |
Gene ID: | 8480 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |