The mRNA Capping Enzyme Polyclonal Antibody (CAB6431) is a valuable tool for researchers studying mRNA capping processes. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By binding specifically to the mRNA capping enzyme, this antibody enables the detection and analysis of mRNA capping enzyme levels in various cell types.The mRNA capping enzyme is essential for the proper function of mRNA molecules, playing a key role in gene expression regulation.
Dysregulation of mRNA capping has been implicated in various diseases, including cancer and neurological disorders, making this enzyme a target of interest for researchers in these fields. By using the mRNA Capping Enzyme Polyclonal Antibody, scientists can gain insights into the mechanisms underlying mRNA capping and its implications for disease development and progression.
Product Name:
RNGTT Rabbit Polyclonal Antibody
SKU:
CAB6431
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-260 of human RNGTT (NP_003791.3).
Enables mRNA guanylyltransferase activity and triphosphatase activity. Involved in 7-methylguanosine mRNA capping. Predicted to be located in nucleoplasm.
Purification Method:
Affinity purification
Gene ID:
8732
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using RNGTT antibody (CAB6431) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.