The MRM3 Polyclonal Antibody (CAB4816) is designed for research involving MRM3, a protein involved in mitochondrial function and metabolism. The antibody, raised in rabbits, is highly specific for human samples and has been validated for use in various applications including Western blot, immunofluorescence, and immunohistochemistry. MRM3 is a crucial component of the mitochondrial ribosome, playing a key role in protein synthesis within the mitochondria. Its involvement in energy production and metabolism makes it a target of interest in studies related to metabolic diseases, mitochondrial disorders, and cancer research.
By using the MRM3 Polyclonal Antibody, researchers can detect and analyze MRM3 expression in different cell types and tissues, providing valuable insights into its function and potential implications in various physiological and pathological conditions. This antibody is a valuable tool for researchers looking to further investigate the role of MRM3 in mitochondrial biology and its impact on human health.
Product Name:
MRM3 Rabbit Polyclonal Antibody
SKU:
CAB4816
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-420 of human MRM3 (NP_060616.1).
Efficient translation of mitochondrial-derived transcripts requires proper assembly of the large subunit of the mitochondrial ribosome. Central to the biogenesis of this large subunit is the A-loop of mitochondrial 16S rRNA, which is modified by three rRNA methyltransferases located near mtDNA nucleoids. The protein encoded by this gene methylates G(1370) of 16S rRNA, and this modification is necessary for proper ribosomal large subnit assembly. Two transcript variants encoding different isoforms have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
55178
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using MRM3 Rabbit pAb (CAB4816) at 1:3000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
