The MRI1 Polyclonal Antibody (CAB14344) is a valuable tool for researchers studying the MRI1 protein, a key player in mitochondrial function and metabolism. This antibody, produced in rabbits, exhibits high specificity and sensitivity towards human samples, making it an ideal choice for Western blot applications. By binding to the MRI1 protein, this antibody enables the detection and analysis of MRI1 in various cell types, providing valuable insights into its role in cellular processes related to energy production and metabolism.MRI1, also known as N-methylpyristoyl transferase 1, is essential for the biogenesis of mitochondrial ribosomes and plays a crucial role in mitochondrial translation.
Dysregulation of MRI1 has been implicated in various diseases, including metabolic disorders and cancer. As such, understanding the function and regulation of MRI1 is essential for developing targeted therapies and interventions for these conditions.Researchers in the fields of biochemistry, cell biology, and molecular biology can benefit from the use of the MRI1 Polyclonal Antibody (CAB14344) in their investigations into mitochondrial function and metabolic pathways. Its reliability and accuracy make it a valuable asset for studies aimed at unraveling the complexities of MRI1 and its impact on cellular health and disease.
Product Name:
MRI1 Rabbit Polyclonal Antibody
SKU:
CAB14344
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-369 of human MRI1 (NP_001026897.1).
This enzyme functions in the methionine salvage pathway by catalyzing the interconversion of methylthioribose-1-phosphate and methythioribulose-1-phosphate. Elevated expression of the encoded protein is associated with metastatic melanoma and this protein promotes melanoma cell invasion independent of its enzymatic activity. Mutations in this gene may be associated with vanishing white matter disease (VMWD).
Purification Method:
Affinity purification
Gene ID:
84245
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using MRI1 Rabbit pAb (CAB14344) at 1:3000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.
