The MRGPRX4 Polyclonal Antibody (PACO02437) is a valuable tool for researchers studying MRGPRX4, a G-protein coupled receptor involved in sensory nerve signaling and pain perception. This antibody, raised in rabbits, exhibits high specificity and sensitivity towards human samples and has been validated for use in various research applications, including Western blot and immunohistochemistry.MRGPRX4 is known to play a role in mediating responses to diverse stimuli, including pain, itch, and inflammation.
Its involvement in sensory neuron signaling makes it a promising target for studies related to pain management, neuropathy, and inflammatory diseases. By utilizing the MRGPRX4 Polyclonal Antibody, researchers can effectively detect and analyze MRGPRX4 expression in different cell types and tissues, facilitating a deeper understanding of its function and potential therapeutic implications in the field of neuroscience and pain research.
Antibody Name:
MRGPRX4 Antibody
Antibody SKU:
PACO02437
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, WB, IF
Recommended Dilutions:
WB:1:500-1:2000, IF:1:200-1:1000
Species Reactivity:
Human
Immunogen:
synthesized peptide derived from the C-terminal region of human MRGX4.
Form:
Liquid
Storage Buffer:
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification Method:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
MRGPRX4: Orphan receptor. Probably involved in the function of nociceptive neurons. May regulate nociceptor function and/or development, including the sensation or modulation of pain. Potently activated by enkephalins. Belongs to the G-protein coupled receptor 1 family. Mas subfamily.Protein type: GPCR, family 1; Membrane protein, integral; Receptor, GPCR; Membrane protein, multi-passChromosomal Location of Human Ortholog: 11p15.1Cellular Component: integral to plasma membraneMolecular Function: G-protein coupled receptor activity
