The MrgprX1 Polyclonal Antibody (CAB13142) is a valuable tool for researchers studying MrgprX1, a G protein-coupled receptor involved in the detection of pruritic (itch) stimuli. This antibody, generated in rabbits, demonstrates high reactivity with human samples and is validated for Western blot applications. By binding specifically to the MrgprX1 protein, this antibody enables researchers to detect and analyze its expression in various cell types, making it an ideal choice for investigations in the fields of neurobiology and dermatology.MrgprX1 is known for its role in mediating itch sensations, making it a promising target for the development of treatments for conditions such as chronic itch and pruritus.
Understanding the function of MrgprX1 receptors is crucial for developing therapeutic interventions that can alleviate discomfort and improve the quality of life for individuals suffering from itch-related disorders. This antibody provides researchers with a valuable tool to further explore the mechanisms underlying itch sensations and pave the way for new treatment options.
Product Name:
MRGPRX1 Rabbit Polyclonal Antibody
SKU:
CAB13142
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 263-322 of human MRGPRX1 (NP_671732.3).
Enables transmembrane signaling receptor activity. Involved in cell surface receptor signaling pathway and response to chloroquine. Predicted to be located in cell surface.
Purification Method:
Affinity purification
Gene ID:
259249
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using MRGPRX1 Rabbit pAb (CAB13142) at 1:3000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
