The MRFAP1 Polyclonal Antibody (CAB8739) is a vital tool for researchers studying MRFAP1, a protein involved in chromatin regulation and gene expression. This antibody is produced in rabbits and has been rigorously validated for use in immunohistochemistry and Western blot applications with human samples. By specifically binding to the MRFAP1 protein, this antibody enables the detection and analysis of MRFAP1 in a variety of cell types, making it an essential asset for studies in epigenetics, gene regulation, and cancer research.
MRFAP1, also known as multiple coiled-coil nuclear protein, plays a crucial role in chromatin organization and transcriptional regulation, making it a key player in cellular processes such as DNA replication, repair, and gene expression. Dysregulation of MRFAP1 has been linked to various diseases, including cancer, developmental disorders, and neurodegenerative diseases. By understanding the function and regulation of MRFAP1, researchers can gain valuable insights into disease mechanisms and potential therapeutic targets.
Product Name:
MRFAP1 Rabbit Polyclonal Antibody
SKU:
CAB8739
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-127 of human MRFAP1 (NP_150638.1).
This gene encodes an intracellular protein that interacts with members of the MORF4/MRG (mortality factor on chromosome 4/MORF4 related gene) family and the tumor suppressor Rb (retinoblastoma protein.) The protein may play a role in senescence, cell growth and immortalization. Alternative splicing results in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
93621
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using MRFAP1 antibody (CAB8739) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 60s.
