MRE11 Rabbit Monoclonal Antibody (CAB4222)
- SKU:
- CAB4222
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Epigenetics and Nuclear Signaling
Frequently bought together:
Description
Product Name: | MRE11 Rabbit Monoclonal Antibody |
SKU: | CAB4222 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 400-500 of human MRE11 (P49959). |
Sequence: | RHRE QKEK TGEE INFG KLIT KPSE GTTL RVED LVKQ YFQT AEKN VQLS LLTE RGMG EAVQ EFVD KEEK DAIE ELVK YQLE KTQR FLKE RHID ALED KIDE E |
Tested Applications: | WB ChIP ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 ChIP,5μg antibody for 10μg-15μg of Chromatin |
Synonyms: | ATLD; HNGS1; MRE11A; MRE11B; MRE11 |
Positive Sample: | HeLa,Mouse testis |
Conjugate: | Unconjugated |
Cellular Localization: | Nucleus. |
Calculated MW: | 81kDa |
Observed MW: | 81kDa |
This gene encodes a nuclear protein involved in homologous recombination, telomere length maintenance, and DNA double-strand break repair. By itself, the protein has 3' to 5' exonuclease activity and endonuclease activity. The protein forms a complex with the RAD50 homolog; this complex is required for nonhomologous joining of DNA ends and possesses increased single-stranded DNA endonuclease and 3' to 5' exonuclease activities. In conjunction with a DNA ligase, this protein promotes the joining of noncomplementary ends in vitro using short homologies near the ends of the DNA fragments. This gene has a pseudogene on chromosome 3. Alternative splicing of this gene results in two transcript variants encoding different isoforms.
Purification Method: | Affinity purification |
Gene ID: | 4361 |
Clone Number: | ARC0931 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3. |