Mannose Receptor/CD206 Polyclonal Antibody (CAB8301)
- SKU:
- CAB8301
- Product Type:
- Antibody
- Applications:
- WB
- IHC
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | Mannose Receptor/CD206 Polyclonal Antibody |
SKU: | CAB8301 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 610-860 of human Mannose Receptor/CD206 (NP_002429.1). |
Sequence: | GLWD VLKC DEKA KFVC KHWA EGVT HPPK PTTT PEPK CPED WGAS SRTS LCFK LYAK GKHE KKTW FESR DFCR ALGG DLAS INNK EEQQ TIWR LITA SGSY HKLF WLGL TYGS PSEG FTWS DGSP VSYE NWAY GEPN NYQN VEYC GELK GDPT MSWN DINC EHLN NWIC QIQK GQTP KPEP TPAP QDNP PVTE DGWV IYKD YQYY FSKE KETM DNAR AFCK RNFG DLVS IQSE SEKK FLWK YVNR NDAQ SAY |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:1000 - 1:5000 |
Synonyms: | MMR; hMR; CD206; MRC1L1; CLEC13D; CLEC13DL; bA541I19.1; Mannose Receptor/CD206 |
Positive Sample: | Rat lung |
Conjugate: | Unconjugated |
Cellular Localization: | Cell membrane, Endosome membrane, Single-pass type I membrane protein. |
Calculated MW: | 166kDa |
Observed MW: | 190-250kDa |
The recognition of complex carbohydrate structures on glycoproteins is an important part of several biological processes, including cell-cell recognition, serum glycoprotein turnover, and neutralization of pathogens. The protein encoded by this gene is a type I membrane receptor that mediates the endocytosis of glycoproteins by macrophages. The protein has been shown to bind high-mannose structures on the surface of potentially pathogenic viruses, bacteria, and fungi so that they can be neutralized by phagocytic engulfment.
Purification Method: | Affinity purification |
Gene ID: | 4360 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3. |