The MPP7 Polyclonal Antibody (CAB16598) is a valuable tool for researchers studying MPP7, a protein involved in cell adhesion and signaling pathways. Produced in rabbits, this antibody demonstrates high reactivity with human samples and is validated for use in Western blot applications. By binding specifically to the MPP7 protein, this antibody facilitates the detection and analysis of MPP7 in a variety of cell types, making it ideal for studies in cell biology and cancer research.
MPP7, also known as MAGI-3, plays a crucial role in cell-cell adhesion and signal transduction processes. Its involvement in these pathways makes it a key player in cellular function and potentially a target for therapeutic interventions in diseases such as cancer and neurological disorders. By studying the function and regulation of MPP7, researchers can gain valuable insights into its role in disease progression and potentially identify novel treatment strategies.
Product Name:
MPP7 Rabbit Polyclonal Antibody
SKU:
CAB16598
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 297-576 of human MPP7 (NP_775767.2).
The protein encoded by this gene is a member of the p55 Stardust family of membrane-associated guanylate kinase (MAGUK) proteins, which function in the establishment of epithelial cell polarity. This family member forms a complex with the polarity protein DLG1 (discs, large homolog 1) and facilitates epithelial cell polarity and tight junction formation. Polymorphisms in this gene are associated with variations in site-specific bone mineral density (BMD). Alternative splicing results in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
143098
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from mouse lung, using MPP7 Rabbit pAb (CAB16598) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.