The MPP6 Polyclonal Antibody (CAB10509) is a valuable tool for researchers studying MPP6, a protein involved in RNA metabolism and splicing. This antibody, raised in rabbits, is highly specific to MPP6 in human samples and has been validated for use in Western blot applications. By targeting MPP6, this antibody allows for the detection and analysis of this protein in various cell types, making it ideal for research in molecular biology and RNA splicing mechanisms.MPP6 is a key player in the regulation of RNA splicing processes, making it a crucial component in gene expression and protein production. Dysregulation of MPP6 has been linked to various diseases, including cancer and genetic disorders, highlighting the importance of studying its function.
By understanding the role of MPP6, researchers can gain insights into the mechanisms underlying these diseases and potentially develop targeted therapies to address them.Overall, the MPP6 Polyclonal Antibody (CAB10509) serves as a valuable tool for researchers investigating the functions of MPP6 in cellular processes and disease pathways. Its specificity and reliability make it a trusted reagent for studies focusing on RNA metabolism, splicing, and related mechanisms.
Product Name:
MPP6 Rabbit Polyclonal Antibody
SKU:
CAB10509
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 220-420 of human MPP6 (NP_057531.2).
Members of the peripheral membrane-associated guanylate kinase (MAGUK) family function in tumor suppression and receptor clustering by forming multiprotein complexes containing distinct sets of transmembrane, cytoskeletal, and cytoplasmic signaling proteins. All MAGUKs contain a PDZ-SH3-GUK core and are divided into 4 subfamilies, DLG-like (see DLG1; MIM 601014), ZO1-like (see TJP1; MIM 601009), p55-like (see MPP1; MIM 305360), and LIN2-like (see CASK; MIM 300172), based on their size and the presence of additional domains. MPP6 is a member of the p55-like MAGUK subfamily (Tseng et al., 2001 [PubMed 11311936]).
Purification Method:
Affinity purification
Gene ID:
51678
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using MPP6 antibody (CAB10509) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.
