MPP1 Rabbit Polyclonal Antibody (CAB6298)
- SKU:
- CAB6298
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Description
Product Name: | MPP1 Rabbit Polyclonal Antibody |
SKU: | CAB6298 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-270 of human MPP1 (NP_002427.1). |
Sequence: | MTLK ASEG ESGG SMHT ALSD LYLE HLLQ KRSR PEAV SHPL NTVT EDMY TNGS PAPG SPAQ VKGQ EVRK VRLI QFEK VTEE PMGI TLKL NEKQ SCTV ARIL HGGM IHRQ GSLH VGDE ILEI NGTN VTNH SVDQ LQKA MKET KGMI SLKV IPNQ QSRL PALQ MFMR AQFD YDPK KDNL IPCK EAGL KFAT GDII QIIN KDDS NWWQ GRVE GSSK ESAG LIPS PELQ EWRV ASMA QSAP SEAP SCSP FGKK KKYK DKYL AKHS SIFD QLDV VS |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | MRG1; PEMP; AAG12; EMP55; DXS552E; MPP1 |
Positive Sample: | 293T,Mouse kidney,Mouse thymus |
Conjugate: | Unconjugated |
Cellular Localization: | Cell projection, Lipid-anchor, Membrane, stereocilium. |
Calculated MW: | 52kDa |
Observed MW: | 52kDa |
This gene encodes the prototype of the membrane-associated guanylate kinase (MAGUK) family proteins. MAGUKs interact with the cytoskeleton and regulate cell proliferation, signaling pathways, and intercellular junctions. The encoded protein is an extensively palmitoylated membrane phosphoprotein containing a PDZ domain, a Src homology 3 (SH3) motif, and a guanylate kinase domain. This gene product interacts with various cytoskeletal proteins and cell junctional proteins in different tissue and cell types, and may be involved in the regulation of cell shape, hair cell development, neural patterning of the retina, and apico-basal polarity and tumor suppression pathways in non-erythroid cells. Multiple transcript variants encoding different isoforms have been found for this gene.
Purification Method: | Affinity purification |
Gene ID: | 4354 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |