The MPG Polyclonal Antibody (CAB18070) is a powerful tool for researchers studying the protein MPG, which plays a crucial role in DNA repair and the maintenance of genomic stability. This antibody, derived from rabbits, exhibits high specificity and sensitivity when used in Western blot experiments, allowing for accurate detection and analysis of MPG in various cell types.MPG is a key enzyme involved in the base excision repair pathway, repairing DNA damage caused by alkylating agents and oxidative stress. Dysregulation of MPG has been linked to increased genomic instability and cancer development, making it a promising target for cancer therapy and personalized medicine approaches.
By utilizing the MPG Polyclonal Antibody, researchers can gain valuable insights into the function and regulation of MPG in cellular processes, facilitating advancements in cancer research, drug development, and precision medicine strategies. This antibody is a valuable tool for scientists aiming to unravel the complexities of DNA repair mechanisms and their implications for human health.
Product Name:
[KO Validated] MPG Rabbit Polyclonal Antibody
SKU:
CAB18070
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-293 of human MPG (NP_001015052.1).
Predicted to enable alkylbase DNA N-glycosylase activity. Predicted to be involved in base-excision repair. Located in cytosol and nucleoplasm.
Purification Method:
Affinity purification
Gene ID:
4350
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from wild type (WT) and MPG knockout (KO) HeLa cells, using [KO Validated] MPG Rabbit pAb (CAB18070) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 60s.
