The MOV10L1 Polyclonal Antibody (PACO01080) is a specialized research tool designed for investigating the MOV10L1 protein, an RNA helicase that plays a key role in post-transcriptional gene regulation. This antibody, produced in rabbits, exhibits high specificity and sensitivity for detecting MOV10L1 in human samples, making it a valuable tool for various molecular biology and cell biology experiments.MOV10L1 is known for its involvement in RNA processing and gene silencing pathways, making it a significant target for studies related to RNA biology, epigenetics, and gene expression regulation. By using the MOV10L1 Polyclonal Antibody in techniques such as Western blotting or immunofluorescence, researchers can analyze the expression and localization of MOV10L1 in different cell types and experimental conditions, providing insights into its function and potential therapeutic applications.
The role of MOV10L1 in post-transcriptional gene regulation and its connection to processes like RNA interference and microRNA-mediated gene silencing make it a compelling molecule for exploring novel therapeutic strategies in areas such as cancer research, viral infections, and neurodegenerative diseases. By leveraging the MOV10L1 Polyclonal Antibody, researchers can delve deeper into the mechanisms underlying these conditions and pave the way for innovative treatments targeting MOV10L1 pathways.
Antibody Name:
MOV10L1 Antibody
Antibody SKU:
PACO01080
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, WB, IHC
Recommended Dilutions:
WB:1:500-1:2000, IHC:1:100-1:300
Species Reactivity:
Human
Immunogen:
synthesized peptide derived from the Internal region of human MOV10L1.
Form:
Liquid
Storage Buffer:
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification Method:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
Synonyms:
MOV10L1; Putative helicase Mov10l1; Moloney leukemia virus 10-like protein 1; MOV10-like protein 1
UniProt Protein Function:
MOV10L1: Putative RNA helicase. Isoform 1 may play a role in male germ cell development. Belongs to the DNA2/NAM7 helicase family. SDE3 subfamily. 3 isoforms of the human protein are produced by alternative splicing.Protein type: Helicase; EC 3.6.4.13Chromosomal Location of Human Ortholog: 22q13.33Cellular Component: intracellularMolecular Function: RNA binding; magnesium ion binding; ATP binding; ATP-dependent RNA helicase activityBiological Process: multicellular organismal development; spermatogenesis; gene expression; germ cell development
UniProt Protein Details:
NCBI Summary:
This gene is similar to a mouse gene that encodes a putative RNA helicase and shows testis-specific expression. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2009]
