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Mouse Ythdc1 Polyclonal Antibody (CAB24548)

SKU:
CAB24548
€129
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Description

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Product Name:Mouse Ythdc1 Polyclonal Antibody
SKU:CAB24548
Size:20uL, 100uL
Isotype:IgG
Host Species:Rabbit
Reactivity:Mouse
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 597-736 of mouse Ythdc1 (NP_808348.2).
Sequence:SYND YVRE FHNM GPPP PWQG MPPY PGIE QPPH HPYY QHHA PPPQ AHPP YSGH HPVP HEAR YRDK RVHD YDMR VDDF LRRT QAVV SGRR SRPR ERDR ERER DRPR DNRR DRER DRGR DRER ERER ICDR DRDR GERG RYRR
Tested Applications:WB ELISA
Recommended Dilution:WB,1:1000 - 1:5000
Synonyms:mKIAA1966; A730098D12Rik; Mouse Ythdc1
Positive Sample:NIH/3T3
Conjugate:Unconjugated
Cellular Localization:Nucleus. Localizes to a novel subnuclear structure, the YT bodies.
Calculated MW:85kDa
Observed MW:110kDa

Predicted to enable N6-methyladenosine-containing RNA binding activity and mRNA binding activity. Involved in posttranscriptional regulation of gene expression. Acts upstream of or within gamete generation; in utero embryonic development; and regulation of mRNA processing. Located in nucleus. Orthologous to human YTHDC1 (YTH domain containing 1).

Purification Method:Affinity purification
Gene ID:231386
Storage Buffer:Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Product ImageWestern blot analysis of lysates from NIH/3T3 cells, using Mouse Ythdc1 Rabbit pAb (CAB24548) at 1:2000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 60s.

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