The Mouse YTHDC1 Polyclonal Antibody is a valuable tool for researchers studying YTHDC1, a RNA-binding protein that plays a role in RNA metabolism and regulation. This antibody, produced in rabbits, shows high reactivity with mouse samples and is validated for use in Western blotting and immunohistochemistry applications. By binding specifically to the YTHDC1 protein, researchers can detect and analyze its expression in various tissues and cell types.YTHDC1 is known for its involvement in mRNA splicing and processing, as well as its regulation of gene expression. Its function in RNA metabolism has implications for a wide range of biological processes, including development, differentiation, and disease.
Researchers studying RNA biology, gene regulation, and developmental biology will find this antibody particularly useful for their experiments.Furthermore, the understanding of YTHDC1's role in RNA biology and gene regulation has significant implications for diseases such as cancer, neurological disorders, and developmental abnormalities. By uncovering the mechanisms by which YTHDC1 influences gene expression and RNA processing, researchers can potentially identify novel therapeutic targets and develop new treatment strategies for these conditions.
Product Name:
Mouse Ythdc1 Polyclonal Antibody
SKU:
CAB24548
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 597-736 of mouse Ythdc1 (NP_808348.2).
Nucleus. Localizes to a novel subnuclear structure, the YT bodies.
Calculated MW:
85kDa
Observed MW:
110kDa
Predicted to enable N6-methyladenosine-containing RNA binding activity and mRNA binding activity. Involved in posttranscriptional regulation of gene expression. Acts upstream of or within gamete generation; in utero embryonic development; and regulation of mRNA processing. Located in nucleus. Orthologous to human YTHDC1 (YTH domain containing 1).
Purification Method:
Affinity purification
Gene ID:
231386
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of lysates from NIH/3T3 cells, using Mouse Ythdc1 Rabbit pAb (CAB24548) at 1:2000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 60s.
