The Mouse TCR Monoclonal Antibody (APC Conjugated, H57-597, HB218) is a powerful tool for studying T cell receptor (TCR) expression and function in mouse samples. This antibody, conjugated to allophycocyanin (APC), specifically targets the TCR complex, allowing for precise detection and analysis in various experimental settings. The H57-597 and HB218 clones are well-characterized monoclonal antibodies known for their high specificity and reliability in recognizing TCR molecules. This conjugated antibody is especially useful in flow cytometry applications, where it can facilitate the identification and characterization of TCR-expressing cell subsets.
Research involving TCR signaling, activation, and diversity, particularly in the context of immune responses and autoimmunity, can greatly benefit from the use of this APC-conjugated antibody. Its validation for mouse samples ensures consistent and reproducible results, making it an essential reagent for immunology studies and immune-related research projects.
Product Title:
APC Anti-Mouse TCRβ Antibody [H57-597 (HB218)]
SKU:
AGEL1549
Size:
25µg, 100µg
Clone No:
H57-597 (HB218)
Synonyms:
TCR-β chain; TCR-β; β-TCR;
Host Species:
Armenian Hamster
Reactivity:
Mouse
Application:
FCM
Isotype:
Armenian Hamster IgG
Isotype Control:
APC Armenian Hamster IgG Isotype Control[PIP]
Form:
Liquid
Conjugation:
APC
Recommended Use:
Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/106 cells in 100 μL volume].
Spectrum:
Gene ID:
21577
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
T cell receptor (TCR) is a heterodimer consisting of an α and a β chain (TCR α/β) or a γ and a δ chain (TCR γ/δ). TCR-β is a member of the immunoglobulin superfamily and a component of the CD3/TCR complex (along with TCR-α). It is expressed on α/β TCR-bearing T cells and thymocytes. The CD3/TCR complex plays a key role in antigen recognition, signal transduction, and T cell activation.