Mouse MIP-1 Gamma Recombinant Protein (RPPB1220)
- SKU:
- RPPB1220
- Product Type:
- Recombinant Protein
- Species:
- Mouse
- Uniprot:
- P51670
- Research Area:
- Chemokines
Frequently bought together:
Description
| Product Name: | Mouse MIP-1 Gamma Recombinant Protein |
| Product Code: | RPPB1220 |
| Size: | 20µg |
| Species: | Mouse |
| Target: | MIP-1 Gamma |
| Synonyms: | CCL9/10, MRP2, CCF18. |
| Source: | Escherichia Coli |
| Physical Appearance: | Sterile Filtered White lyophilized (freeze-dried) powder. |
| Formulation: | The MIP-1 gamma was lyophilized from 1xPBS solution pH-7.4. |
| Solubility: | It is recommended to reconstitute the lyophilized MIP-1 gamma in sterile 18M-cm H2O not less than 100�g/ml, which can then be further diluted to other aqueous solutions. |
| Stability: | Lyophilized MIP-1 gamma although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution CCL9/10 should be stored at 4°C between 2-7 days and for future use below -18°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles. |
| Purity: | Greater than 97.0% as determined by:(a) Analysis by RP-HPLC.(b) Analysis by SDS-PAGE. |
| Amino Acid Sequence: | QITHATETKE VQSSLKAQQG LEIEMFHMGF QDSSDCCLSY NSRIQCSRFI GYFPTSGGCT RPGIIFISKR GFQVCANPSD RRVQRCIERL EQNSQPRTYK Q |
| Biological Activity: | Defined by its ability to chemoattract human neutrophils using a concentration range of 0.1-10 ng/ml, corresponding to a Specific Activity of 10,000-100,000IU/mg. |
Mouse MIP-1 gamma is 75% identical in its amino acid compostion as compared to the rat specie. MIP-1 gamma is a CC chemokine localized in murine blood and a widespread range of murine tissues, without having an identified human homolog. MIP-1 gamma signals through the CCR1 receptor. MIP-1 gamma chemoattracts neutrophils and also inhibits colony formation of bone marrow myeloid immature progenitors. MIP-1 gamma has six cysteines including the four highly conserved cysteine residues present in CC chemokines.
MIP-1 gamma Mouse Recombinant produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 101 amino acids and having a molecular mass of 11.6 kDa. The MIP-1 gamma is purified by proprietary chromatographic techniques.
| UniProt Protein Function: | CCL9: Monokine with inflammatory, pyrogenic and chemokinetic properties. Circulates at high concentrations in the blood of healthy animals. Binding to a high-affinity receptor activates calcium release in neutrophils. It also inhibits colony formation of bone marrow myeloid immature progenitorsProtein type: CytokineCellular Component: extracellular space; extracellular regionMolecular Function: chemokine activity; cytokine activityBiological Process: immune response; negative regulation of myoblast differentiation; chemotaxis |
| UniProt Protein Details: | |
| NCBI Summary: | |
| UniProt Code: | P51670 |
| NCBI GenInfo Identifier: | 1709026 |
| NCBI Gene ID: | 20308 |
| NCBI Accession: | P51670.1 |
| UniProt Secondary Accession: | P51670,Q5QNW2 |
| UniProt Related Accession: | P51670 |
| Molecular Weight: | 13,871 Da |
| NCBI Full Name: | C-C motif chemokine 9 |
| NCBI Synonym Full Names: | chemokine (C-C motif) ligand 9 |
| NCBI Official Symbol: | Ccl9�� |
| NCBI Official Synonym Symbols: | CCF18; MRP-2; Scya9; Scya10�� |
| NCBI Protein Information: | C-C motif chemokine 9; MIP-1 gamma; small inducible cytokine A9; small inducible cytokine A10; macrophage inflammatory protein 1-gamma; macrophage inflammatory protein-related protein 2 |
| UniProt Protein Name: | C-C motif chemokine 9 |
| UniProt Synonym Protein Names: | CCF18; Macrophage inflammatory protein 1-gamma; MIP-1-gamma; Macrophage inflammatory protein-related protein 2; MRP-2; Small-inducible cytokine A9Cleaved into the following 3 chains:CCL9(29-101); CCL9(30-101); CCL9(31-101) |
| Protein Family: | C-C motif chemokine |
| UniProt Gene Name: | Ccl9�� |
| UniProt Entry Name: | CCL9_MOUSE |
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