PE/Cyanine5.5 Anti-Mouse MHC II (I-A/I-E) Antibody [M5/114]
The Mouse MHC II (I-A, I-E) Monoclonal Antibody PE/Cyanine5.5 Conjugated (M5/114) (AGEL0505) is a powerful tool for researchers studying the major histocompatibility complex (MHC) class II in mouse models. This monoclonal antibody, conjugated with both PE and Cyanine5.5 fluorophores, specifically targets MHC II molecules I-A and I-E, allowing for precise detection and analysis in flow cytometry and immunofluorescence applications.MHC class II molecules play a crucial role in antigen presentation and immune response regulation. The M5/114 antibody offers high specificity and sensitivity, making it an ideal choice for identifying and studying MHC II-expressing cells in various tissues and biological samples.
Whether investigating immune responses, inflammatory processes, or immune-related disorders, this antibody provides reliable results and valuable insights into MHC II functionality in mouse models.With its validated performance and robust reactivity, the Mouse MHC II (I-A, I-E) Monoclonal Antibody PE/Cyanine5.5 Conjugated (M5/114) (AGEL0505) is a key tool for researchers in immunology, infectious diseases, and vaccine development. Enhance your research with this versatile antibody designed to uncover the complexities of MHC class II biology in mouse systems.
Product Title:
PE/Cyanine5.5 Anti-Mouse MHC II (I-A/I-E) Antibody [M5/114]
SKU:
AGEL0505
Size:
25µg, 100µg
Clone No:
M5/114
Synonyms:
H2-Ab1/Eb1;Major histocompatibility protein class II beta chain;MHC class II H2-IA-beta-psi;I-E beta MHC class II;MHC class II;
Host Species:
Rat
Reactivity:
Mouse
Application:
FCM
Isotype:
Rat IgG2b, κ
Isotype Control:
PE/Cyanine5.5 Rat IgG2b, κ Isotype Control[LTF-2]
Form:
Liquid
Conjugation:
PE/Cyanine 5.5
Recommended Use:
Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/106 cells in 100 μL volume].
Spectrum:
Swissprot:
P14483 O78196
Gene ID:
14961,14969
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
These class II molecules are expressed on antigen presenting cells (including B cells) and a subset of T cells from H-2b,d,q,r bearing mice and are involved in antigen presentation to T cells expressing CD3/TCR and CD4 proteins.