PE/Cyanine5.5 Anti-Mouse MHC II (I-A/I-E) Antibody [M5/114]
The Mouse MHC II/I-A/I-E Monoclonal Antibody (PE-Cyanine5.5 Conjugated) - M5/114 (AGEL0496) offered by AssayGenie is a high-quality antibody specifically designed for researchers conducting studies related to major histocompatibility complex (MHC) class II molecules in mice. This monoclonal antibody is conjugated with PE-Cyanine5.5, enabling easy detection and analysis in flow cytometry applications.MHC class II molecules play a crucial role in the immune system by presenting antigens to T-cells, thus initiating adaptive immune responses. The M5/114 antibody targets the I-A and I-E subtypes of MHC II, making it a valuable tool for investigating antigen presentation and immune responses in mouse models.
Its specificity and sensitivity make it an essential reagent for immunology research, including studies on autoimmune diseases, transplant rejection, and infectious diseases.By using the Mouse MHC II/I-A/I-E Monoclonal Antibody (PE-Cyanine5.5 Conjugated) - M5/114 (AGEL0496), researchers can gain valuable insights into the workings of the immune system in mice, aiding in the development of new therapeutic approaches and potential treatments for a variety of immune-related conditions.
Product Title:
PE/Cyanine5.5 Anti-Mouse MHC II (I-A/I-E) Antibody [M5/114]
SKU:
AGEL0496
Size:
50 Tests, 100 Tests, 200 Tests
Clone No:
M5/114
Synonyms:
H2-Ab1/Eb1;Major histocompatibility protein class II beta chain;MHC class II H2-IA-beta-psi;I-E beta MHC class II;MHC class II;
Host Species:
Rat
Reactivity:
Mouse
Application:
FCM
Isotype:
Rat IgG2b, κ
Isotype Control:
PE/Cyanine5.5 Rat IgG2b, κ Isotype Control[LTF-2]
Form:
Liquid
Conjugation:
PE/Cyanine 5.5
Recommended Use:
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:
Swissprot:
P14483 O78196
Gene ID:
14961,14969
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
These class II molecules are expressed on antigen presenting cells (including B cells) and a subset of T cells from H-2b,d,q,r bearing mice and are involved in antigen presentation to T cells expressing CD3/TCR and CD4 proteins.