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FITC Anti-Mouse MHC II (I-A/I-E) Antibody [M5/114] (AGEL0499)

SKU:
AGEL0499
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Applications:
FC
Reactivity:
Mouse
Host Species:
Rat
Isotype:
IgG2a,k
Clone:
M5/114
Conjugation:
FITC
€109 - €199
Frequently bought together:

Description

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FITC Anti-Mouse MHC II (I-A/I-E) Antibody [M5/114]

The Mouse MHC II (I-A/I-E) Monoclonal Antibody (FITC Conjugated, M5/114) is a valuable tool for researchers studying the Major Histocompatibility Complex Class II in mice. This monoclonal antibody, conjugated with FITC for fluorescent detection, specifically targets the I-A and I-E proteins within the MHC II complex, enabling precise identification and analysis.The MHC II complex is a critical component of the immune system, responsible for presenting antigens to T cells and initiating immune responses. The M5/114 antibody is designed to recognize and bind to these specific MHC II proteins, allowing researchers to investigate their expression levels and distribution in various mouse tissues and cell types.

This antibody is highly specific and validated for use in techniques such as flow cytometry and immunofluorescence, providing reliable results for experiments related to immunology, infectious diseases, and autoimmune disorders. By targeting MHC II I-A/I-E molecules, researchers can gain insights into immune activation, antigen presentation, and immune cell interactions in mouse models.Overall, the Mouse MHC II (I-A/I-E) Monoclonal Antibody (FITC Conjugated, M5/114) is a powerful tool for exploring the role of MHC II in immune responses and advancing understanding of immune-related processes in mouse research models.

Product Title:FITC Anti-Mouse MHC II (I-A/I-E) Antibody [M5/114]
SKU:AGEL0499
Size:25µg, 100µg
Clone No:M5/114
Synonyms:H2-Ab1/Eb1;Major histocompatibility protein class II beta chain;MHC class II H2-IA-beta-psi;I-E beta MHC class II;MHC class II;
Host Species:Rat
Reactivity:Mouse
Application:FCM
Isotype:Rat IgG2b, κ
Isotype Control:FITC Rat IgG2b, κ Isotype Control[LTF-2]
Form:Liquid
Conjugation:FITC
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/106 cells in 100 μL volume].
Spectrum:Spectrum Image
Swissprot:P14483 O78196
Gene ID:14961,14969
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:These class II molecules are expressed on antigen presenting cells (including B cells) and a subset of T cells from H-2b,d,q,r bearing mice and are involved in antigen presentation to T cells expressing CD3/TCR and CD4 proteins.

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