The Mouse Ly6G Monoclonal Antibody PE-Cy5 Conjugated (1A8) is a valuable tool for researchers studying immune responses and inflammatory processes. This antibody, conjugated to PE-Cy5 for easy detection and analysis, targets the Ly6G protein found on the surface of neutrophils, a key player in the immune system's defense against pathogens.The 1A8 antibody, derived from mice, is highly specific and sensitive, making it ideal for applications such as flow cytometry and immunofluorescence. Its ability to bind to Ly6G enables researchers to identify and study neutrophils in various experimental setups, providing insights into their functions in infection, inflammation, and autoimmune diseases.
Neutrophils are crucial for the body's immediate response to infections, and dysregulation of their activity can lead to various diseases, including sepsis and autoimmune disorders. By using the Mouse Ly6G Monoclonal Antibody PE-Cy5 Conjugated (1A8), researchers can deepen their understanding of neutrophil biology and potentially uncover new targets for therapeutic interventions aimed at modulating immune responses and inflammation.
Product Title:
PE/Cyanine5 Anti-Mouse Ly6G Antibody [1A8]
SKU:
AGEL0395
Size:
50 Tests, 100 Tests, 200 Tests
Clone No:
1A8
Synonyms:
Lymphocyte antigen 6G;Ly-6G;Ly-6G.1;Ly6g;
Host Species:
Rat
Reactivity:
Mouse
Application:
FCM
Isotype:
Rat IgG2a, κ
Isotype Control:
PE/Cyanine5 Rat IgG2a, κ Isotype Control[2A3]
Form:
Liquid
Conjugation:
PE/Cyanine 5
Recommended Use:
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:
Swissprot:
P35461
Gene ID:
546644
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
Lymphocyte antigen 6 complex, locus G (Ly-6G), a 21-25 kD GPI-anchored protein, is expressed on the majority of myeloid cells in bone marrow and peripheral granulocytes.