The Mouse LY6C Monoclonal Antibody (AF488 Conjugated, mONts-1) is a vital tool for researchers studying immune responses and inflammatory processes in mouse models. This monoclonal antibody, labeled with AF488 for fluorescent microscopy applications, specifically targets the LY6C protein, a marker of inflammatory monocytes and neutrophils.LY6C is a crucial cell surface antigen involved in regulating immune cell recruitment and function during inflammation. By utilizing this antibody, researchers can effectively track and visualize LY6C-expressing cells in various tissues and experimental conditions. This antibody is ideal for flow cytometry, immunofluorescence, and immunohistochemistry studies aimed at elucidating the role of LY6C-positive cells in immune-related diseases such as infections, autoimmune disorders, and cancer.
The Mouse LY6C Monoclonal Antibody (AF488 Conjugated, mONts-1) offers high sensitivity and specificity, providing reliable results for diverse experimental settings. Its utility in identifying and characterizing inflammatory cell populations makes it an invaluable tool for researchers investigating the complex interplay between immune cells and disease pathology in mouse models.
Product Title:
GenieFluor 488 Anti-Mouse Ly6C Antibody [Monts 1]
SKU:
AGEL1510
Size:
25µg, 100µg
Clone No:
Monts 1
Synonyms:
Lymphocyte antigen 6 complex; locus C;Ly 6C;Ly6c1;Ly6c2;
Host Species:
Rat
Reactivity:
Mouse
Application:
FCM
Isotype:
Rat IgG2a, κ
Isotype Control:
Genie Fluor 488 Rat IgG2a, κ Isotype Control[2A3]
Form:
Liquid
Conjugation:
Genie Fluor488
Recommended Use:
Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/106 cells in 100 μL volume].
Spectrum:
Swissprot:
P0CW03
Gene ID:
17067
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
Most hematopoietic cells express one or more members of Ly-6 family. The expression of Ly-6 varies with development stage and activation. Ly-6C is a 14-17 kD GPI-linked surface protein expressed on mouse monocyte/macrophage cells, endothelial cells, neutrophils, and some T cell subsets. Ly-6C is reported to be an indicator of memory CD8+ T cells.