The Mouse IL-4 Monoclonal Antibody (PE-conjugated, 11B11) is a powerful tool for researchers studying immune responses and cytokine signaling pathways in mice. IL-4 is a key cytokine that plays a crucial role in regulating immune cell differentiation and function, making this antibody essential for investigations in immunology, inflammation, and allergy research.The 11B11 antibody is monoclonal, ensuring high specificity and consistency in results. By being conjugated with PE (Phycoerythrin), it allows for easy detection and quantification of IL-4 expression in flow cytometry and other fluorescence-based assays. This antibody has been extensively validated for its performance in mouse samples, providing reliable data for diverse experimental setups.
IL-4, known for its involvement in promoting Th2 cell differentiation and regulating antibody production, is a key player in modulating immune responses. By targeting IL-4 with the 11B11 antibody, researchers can gain insights into the complex interplay of cytokines in immune regulation and potential therapeutic strategies for conditions such as asthma, allergies, and autoimmune diseases.Overall, the Mouse IL-4 Monoclonal Antibody (PE-conjugated, 11B11) is a valuable tool for unraveling the intricacies of immune system function in mouse models, offering precise detection and analysis capabilities crucial for advancing research in immunology and related fields.
Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/106 cells in 100 μL volume].
Spectrum:
Swissprot:
P07750
Gene ID:
16189
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
IL-4 is a pleiotropic cytokine produced by activated T cells, mast cells, and basophils. IL-4 is a potent lymphoid cell growth factor which stimulates the growth and activation of certain B cells and T cells. IL-4 is important for regulation of T helper subset development.