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APC Anti-Mouse IL-4 Antibody [11B11] (AGEL2061)

SKU:
AGEL2061
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Mouse
Applications:
FC
$215 - $575
Frequently bought together:

Description

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APC Anti-Mouse IL-4 Antibody [11B11]

The Mouse IL-4 Monoclonal Antibody (APC-conjugated, 11B11) is a valuable tool for researchers studying interleukin-4 (IL-4) signaling pathways and immune responses in mice. This antibody, clone 11B11, is specifically designed to target and detect mouse IL-4, a key cytokine involved in regulating immune responses, allergic reactions, and inflammation.IL-4 is a crucial factor in polarizing immune responses towards a T-helper 2 (Th2) phenotype, promoting antibody class switching in B cells, and enhancing the activity of eosinophils and mast cells. By using this APC-conjugated monoclonal antibody, researchers can accurately identify and quantify IL-4-producing cells in flow cytometry experiments, allowing for precise analysis of cytokine expression profiles and immune cell populations.

The 11B11 monoclonal antibody is highly specific, providing reliable results in a range of applications, including flow cytometry, immunofluorescence, and immunohistochemistry. Its bright APC conjugate allows for easy detection and quantification of IL-4-expressing cells in complex biological samples, making it an essential tool for immunologists, researchers studying allergy and asthma, and those investigating Th2 immune responses in various disease models.By utilizing the Mouse IL-4 Monoclonal Antibody (APC-conjugated, 11B11), researchers can gain valuable insights into the role of IL-4 in immune-mediated diseases, inflammatory disorders, and host defense mechanisms in mouse models, ultimately advancing our understanding of cytokine regulation and immune system function.

Product Title:APC Anti-Mouse IL-4 Antibody [11B11]
SKU:AGEL2061
Size:25µg, 100µg
Clone No:11B11
Synonyms:Interleukin-4;IL-4;B-cell IgG differentiation factor;B-cell growth factor 1;BSF-1;IGG1 induction factor;
Host Species:Rat
Reactivity:Mouse
Application:ICFCM
Isotype:Rat IgG1, κ
Isotype Control:APC Rat IgG1, κ Isotype Control[HRPN]
Form:Liquid
Conjugation:APC
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/106 cells in 100 μL volume].
Spectrum:Spectrum Image
Swissprot:P07750
Gene ID:16189
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:IL-4 is a pleiotropic cytokine produced by activated T cells, mast cells, and basophils. IL-4 is a potent lymphoid cell growth factor which stimulates the growth and activation of certain B cells and T cells. IL-4 is important for regulation of T helper subset development.

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