Mouse IFNAR1 Recombinant Protein (His Tag) (RPES6619)
- SKU:
- RPES6619
- Product Type:
- Recombinant Protein
- Species:
- Mouse
Frequently bought together:
Description
Product Name: | Mouse IFNAR1 Recombinant Protein (His Tag) |
Product Code: | RPES6619 |
Size: | 20µg |
Species: | Mouse |
Expression Host: | E.coli |
Synonyms: | Interferon alpha/beta receptor 1, IFN-R-1 IFN-alpha/beta receptor 1, Cytokine receptor class-II member 1, Cytokine receptor family 2 member 1, CRF2-1, Type I interferon receptor 1, IFNAR |
Application: | Immunogen |
Mol Mass: | 29.4 kDa |
AP Mol Mass: | 31.66 kDa |
Tag: | N-His |
Purity: | > 85 % as determined by reducing SDS-PAGE. |
Endotoxin Level: | Please contact us for more information. |
Bio Activity: | Testing in progress |
Sequence: | Glu27-Cyc284 |
Accession: | P33896-1 |
Storage: | Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months. |
Shipping: | This product is provided as lyophilized powder which is shipped with ice packs. |
Formulation: | Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. Please refer to the specific buffer information in the printed manual. |
Reconstitution: | Please refer to the printed manual for detailed information. |
Background: | Component of the receptor for type I interferons, including interferons alpha, IFNB1 and IFNW1. Functions in general as heterodimer with IFNAR2 . Type I interferon binding activates the JAK-STAT signaling cascade, and triggers tyrosine phosphorylation of a number of proteins including JAKs, TYK2, STAT proteins and the IFNR alpha- and beta-subunits themselves. Can form an active IFNB1 receptor by itself and activate a signaling cascade that does not involve activation of the JAK-STAT pathway. |