The Mouse IFN-Gamma Monoclonal Antibody (XMG1.2) is a powerful tool designed for researchers studying immune responses and cytokine signaling pathways in mice. This monoclonal antibody, catalog number AGEL0369, specifically targets and detects interferon-gamma (IFN-gamma), a key cytokine involved in immune defense against pathogens and tumor cells.IFN-gamma is a critical mediator of both innate and adaptive immune responses, playing a key role in activating macrophages, enhancing antigen presentation, and promoting the differentiation of T helper cells. The XMG1.2 antibody is well-suited for various applications, including flow cytometry, immunohistochemistry, and ELISA, allowing for precise detection and quantification of IFN-gamma in experimental samples.
By utilizing the XMG1.2 Monoclonal Antibody, researchers can gain valuable insights into the immune system's response to infections, autoimmune diseases, and cancer, advancing our understanding of immune regulation and potential therapeutic targets. With its high specificity and sensitivity, this antibody is a reliable tool for investigating the role of IFN-gamma in diverse biological processes, making it essential for immunology and infectious disease research.
Product Title:
Purified Anti-Mouse IFN-γ Antibody [XMG1.2]
SKU:
AGEL0369
Size:
25µg, 100µg
Clone No:
XMG1.2
Synonyms:
Interferon gamma;Ifng;IFN-gamma;IFNγ;
Host Species:
Rat
Reactivity:
Mouse
Application:
ICFCM;ELISA
Isotype:
Rat IgG1, κ
Isotype Control:
Purified Rat IgG1, κ Isotype Control[HRPN]
Form:
Liquid
Conjugation:
Unconjugated
Recommended Use:
Each lot of this antibody is quality control tested by flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 2.0 µg per 106 cells in 100 µL volume or 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
IFN-γ is a potent multifunctional cytokine which is secreted primarily by activated NK cells and T cells. Originally characterized based on anti-viral activities, IFN-γ also exerts anti-proliferative, immunoregulatory, and proinflammatory activities. IFN-γ can upregulate MHC class I and II antigen expression by antigen-presenting cells.
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