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PerCP Anti-Mouse MHC II (I-A/I-E) Antibody [M5/114] (AGEL0023)

SKU:
AGEL0023
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Mouse
Host Species:
Rat
Isotype:
IgG2b
Clone:
M5/114
Conjugation:
PerCP
Applications:
FC
€139 - €289
Frequently bought together:

Description

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PerCP Anti-Mouse MHC II (I-A/I-E) Antibody [M5/114]

The PerCP-Conjugated Mouse I-A/I-E Monoclonal Antibody (M5/114) is designed for advanced research targeting I-A/I-E, essential molecules within the Major Histocompatibility Complex (MHC) class II system, which are crucial for antigen presentation and activation of immune responses. This monoclonal antibody, generated in mice, is highly specific to mouse I-A/I-E and is validated for use in flow cytometry applications. Its conjugation with PerCP (Peridinin Chlorophyll Protein) ensures bright and stable fluorescence, facilitating precise and reliable detection.I-A/I-E molecules play a pivotal role in the adaptive immune response, primarily through presenting antigens to CD4+ T cells. Their critical function in immune regulation makes them valuable targets for research on autoimmune disorders, chronic inflammatory conditions, and infectious diseases.

The PerCP-Conjugated Mouse I-A/I-E Monoclonal Antibody (M5/114) is an indispensable tool for researchers aiming to uncover the mechanisms of antigen presentation and develop therapies that modulate immune function.By providing accurate and sensitive detection of I-A/I-E molecules, this antibody supports comprehensive studies of immune response pathways, thereby contributing to the development of novel therapeutic strategies for autoimmune diseases and other immune-related conditions. Understanding the activity of I-A/I-E is crucial for creating innovative immunotherapies that leverage or modulate antigen presentation in various disease contexts. This antibody significantly advances immunology and cancer research.

Product Title:PerCP Anti-Mouse MHC II (I-A/I-E) Antibody [M5/114]
SKU:AGEL0023
Size:50 Tests, 100 Tests, 200 Tests
Clone No:M5/114
Synonyms:H2-Ab1/Eb1;Major histocompatibility protein class II beta chain;MHC class II H2-IA-beta-psi;I-E beta MHC class II;MHC class II;
Host Species:Rat
Reactivity:Mouse
Application:FCM
Isotype:Rat IgG2b, κ
Isotype Control:PerCP Rat IgG2b, κ Isotype Control[LTF-2]
Form:Liquid
Conjugation:PerCP
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Swissprot:P14483 O78196
Gene ID:14961,14969
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:These class II molecules are expressed on antigen presenting cells (including B cells) and a subset of T cells from H-2b,d,q,r bearing mice and are involved in antigen presentation to T cells expressing CD3/TCR and CD4 proteins.

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