null

FITC Anti-Human/Mouse CD44 Antibody [IM7] (AGEL1275)

SKU:
AGEL1275
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Applications:
FC
Reactivity:
Human
Mouse
Host Species:
Rat
Isotype:
IgG2a,k
Clone:
IM7
Conjugation:
FITC
€99 - €369
Frequently bought together:

Description

system_update_altDatasheetsystem_update_altMSDS

FITC Anti-Human/Mouse CD44 Antibody [IM7]

The FITC-conjugated IM7-AGEL1275 Mouse Anti-Human CD44 Monoclonal Antibody offered by AssayGenie is a high-quality tool designed for researchers studying CD44, a multifunctional cell surface glycoprotein involved in cell adhesion, migration, and signaling. This monoclonal antibody, derived from mice, is optimized for detecting CD44 in human samples and is particularly suitable for flow cytometry applications.CD44, a prominent cell adhesion molecule with diverse functions in immunity, development, and cancer progression, is known for its role in regulating cell-cell interactions and participating in inflammatory responses. The IM7-AGEL1275 antibody specifically recognizes the CD44 antigen, allowing for precise and reliable detection in various experimental settings.

Its FITC conjugation ensures easy visualization and quantification of CD44-expressing cells, making it an essential tool for immunologists and cancer biologists alike.By targeting CD44, researchers can investigate its involvement in processes such as lymphocyte activation, lymphoid organ development, and tumor metastasis, paving the way for a better understanding of immune regulation and disease pathogenesis. The IM7-AGEL1275 antibody's sensitivity and specificity make it an invaluable asset for exploring the intricate mechanisms of CD44-mediated signaling pathways, ultimately contributing to advancements in immunotherapy and oncology research.

Product Title:FITC Anti-Human/Mouse CD44 Antibody [IM7]
SKU:AGEL1275
Size:20 Tests, 100 Tests, 200 Tests
Clone No:IM7
Synonyms:CD44 antigen;CD44;CDw44;Epican;Phagocytic glycoprotein 1;PGP-1;Phagocytic glycoprotein I;PGP-I;CD44;LHR; MDU2; MDU3; MIC4;
Host Species:Rat
Reactivity:Human;Mouse
Application:FCM
Isotype:Rat IgG2b, κ
Isotype Control:FITC Rat IgG2b, κ Isotype Control[LTF-2]
Form:Liquid
Conjugation:FITC
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Swissprot:P15379 P16070
Gene ID:12505,960
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD44 is a 80-95 kD glycoprotein also known as Hermes, Pgp1, H-CAM, or HUTCH. It is expressed on all leukocytes, endothelial cells, hepatocytes, and mesenchymal cells. As B and T cells become activated or progress to the memory stage, CD44 expression increases from low or mid levels to high levels. Thus, CD44 has been reported to be a valuable marker for memory cell subsets. High CD44 expression on Treg cells has been associated with potent suppressive function via high production of IL-10. CD44 is an adhesion molecule involved in leukocyte attachment to and rolling on endothelial cells, homing to peripheral lymphoid organs and to the sites of inflammation, and leukocyte aggregation.

Related Products