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GenieFluor 647 Anti-Human/Mouse CD44 Antibody [IM7] (AGEL1289)

SKU:
AGEL1289
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Mouse
Applications:
FC
$239 - $491
Frequently bought together:

Description

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GenieFluor 647 Anti-Human/Mouse CD44 Antibody [IM7]

The Mouse Human CD44 Monoclonal Antibody (AF647 Conjugated, IM7) is a powerful tool for research involving CD44, a transmembrane glycoprotein involved in cell adhesion and migration. This monoclonal antibody, conjugated with AF647 for fluorescence applications, is reactive with both mouse and human samples, providing versatility for a range of experimental setups.CD44 is a multifunctional molecule known to play important roles in various physiological and pathological processes, including inflammation, tissue repair, and cancer metastasis. By targeting CD44, researchers can investigate its involvement in cell signaling pathways, metastatic potential, and interactions with the extracellular matrix.

This antibody, clone IM7, specifically binds to CD44, allowing for precise detection and localization of the protein in different cell types and tissues. Its conjugation with AF647 enables easy visualization and quantification of CD44 expression, making it ideal for flow cytometry, immunofluorescence, and other fluorescence-based assays.For studies focusing on cell adhesion, migration, or cancer biology, the Mouse Human CD44 Monoclonal Antibody (AF647 Conjugated, IM7) offers reliable and reproducible results, opening up new avenues for understanding the complex functions of CD44 in health and disease.

Product Title:GenieFluor 647 Anti-Human/Mouse CD44 Antibody [IM7]
SKU:AGEL1289
Size:25µg, 100µg
Clone No:IM7
Synonyms:CD44 antigen;CD44;CDw44;Epican;Phagocytic glycoprotein 1;PGP-1;Phagocytic glycoprotein I;PGP-I;CD44;LHR; MDU2; MDU3; MIC4;
Host Species:Rat
Reactivity:Human;Mouse
Application:FCM
Isotype:Rat IgG2b, κ
Isotype Control:Genie Fluor 647 Rat IgG2b, κ Isotype Control[LTF-2]
Form:Liquid
Conjugation:Genie Fluor647
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/106 cells in 100 μL volume].
Spectrum:Spectrum Image
Swissprot:P15379 P16070
Gene ID:12505,960
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD44 is a 80-95 kD glycoprotein also known as Hermes, Pgp1, H-CAM, or HUTCH. It is expressed on all leukocytes, endothelial cells, hepatocytes, and mesenchymal cells. As B and T cells become activated or progress to the memory stage, CD44 expression increases from low or mid levels to high levels. Thus, CD44 has been reported to be a valuable marker for memory cell subsets. High CD44 expression on Treg cells has been associated with potent suppressive function via high production of IL-10. CD44 is an adhesion molecule involved in leukocyte attachment to and rolling on endothelial cells, homing to peripheral lymphoid organs and to the sites of inflammation, and leukocyte aggregation.

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