GenieFluor 647 Anti-Human/Mouse CD44 Antibody [IM7] (AGEL1289)
- SKU:
- AGEL1289
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Mouse
- Applications:
- FC
Frequently bought together:
Description
Product Title: | GenieFluor 647 Anti-Human/Mouse CD44 Antibody [IM7] |
SKU: | AGEL1289 |
Size: | 25µg, 100µg |
Clone No: | IM7 |
Synonyms: | CD44 antigen;CD44;CDw44;Epican;Phagocytic glycoprotein 1;PGP-1;Phagocytic glycoprotein I;PGP-I;CD44;LHR; MDU2; MDU3; MIC4; |
Host Species: | Rat |
Reactivity: | Human;Mouse |
Application: | FCM |
Isotype: | Rat IgG2b, κ |
Isotype Control: | Genie Fluor 647 Rat IgG2b, κ Isotype Control[LTF-2] |
Form: | Liquid |
Conjugation: | Genie Fluor647 |
Recommended Use: | Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/106 cells in 100 μL volume]. |
Spectrum: | ![]() |
Swissprot: | P15379 P16070 |
Gene ID: | 12505,960 |
Storage Buffer: | Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant. |
Stability & Storage: | Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase. |
Background: | CD44 is a 80-95 kD glycoprotein also known as Hermes, Pgp1, H-CAM, or HUTCH. It is expressed on all leukocytes, endothelial cells, hepatocytes, and mesenchymal cells. As B and T cells become activated or progress to the memory stage, CD44 expression increases from low or mid levels to high levels. Thus, CD44 has been reported to be a valuable marker for memory cell subsets. High CD44 expression on Treg cells has been associated with potent suppressive function via high production of IL-10. CD44 is an adhesion molecule involved in leukocyte attachment to and rolling on endothelial cells, homing to peripheral lymphoid organs and to the sites of inflammation, and leukocyte aggregation. |