The Mouse/Human CD11b Monoclonal Antibody (PERCP-Cyanine5.5 Conjugated, M1/70) is a versatile tool for researchers studying immune responses and cell interactions in both mouse and human samples. This antibody, offered by AssayGenie, is meticulously designed for accurate detection and analysis of CD11b, a key cell surface marker indicative of myeloid cells.CD11b is a part of the integrin family and is critical for various immune functions, including phagocytosis, cell migration, and immune regulation. The CD11b Monoclonal Antibody, conjugated with PERCP-Cyanine5.5, enables precise identification of CD11b-expressing cells in flow cytometry applications.
With its exceptional specificity and sensitivity, researchers can confidently characterize and quantify myeloid cell populations in complex biological samples.Whether investigating immune responses, inflammatory processes, or disease mechanisms, the Mouse/Human CD11b Monoclonal Antibody provides reliable results and valuable insights into the role of myeloid cells in immune modulation. Enhance your research with this high-quality antibody that offers consistent performance and reproducibility, elevating your studies in immunology, cancer research, and beyond.
Integrin alpha-M;Itgam;CD11 antigen-like family member B;CR-3 alpha chain;Leukocyte adhesion receptor MO1;CD11b;
Host Species:
Rat
Reactivity:
Human;Mouse
Application:
FCM
Isotype:
Rat IgG2b, κ
Isotype Control:
PerCP/Cyanine5.5 Rat IgG2b, κ Isotype Control[LTF-2]
Form:
Liquid
Conjugation:
PerCP/Cyanine 5.5
Recommended Use:
Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/106 cells in 100 μL volume].
Spectrum:
Swissprot:
P05555 P11215
Gene ID:
16409,3684
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD11b is a 170 kD glycoprotein also known as αM integrin, Mac-1 α subunit, Mol, CR3, and Ly-40. CD11b is a member of the integrin family, primarily expressed on granulocytes, monocytes/macrophages, dendritic cells, NK cells, and subsets of T and B cells. CD11b non-covalently associates with CD18 (β2 integrin) to form Mac-1. Mac-1 plays an important role in cell-cell interaction by binding its ligands ICAM-1 (CD54), ICAM-2 (CD102), ICAM-4 (CD242), iC3b, and fibrinogen.