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FITC Anti-Mouse/Human CD11b Antibody [M1/70] (AGEL0306)

SKU:
AGEL0306
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Host Species:
Rat
Isotype:
IgG2b
Clone:
M1/70
Conjugation:
FITC
Applications:
FC
$95 - $227
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Description

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FITC Anti-Mouse/Human CD11b Antibody [M1/70]

The Mouse/Human CD11b Monoclonal Antibody (FITC Conjugated) M1/70 (AGEL0306) is a highly specific antibody designed for research involving the CD11b protein, a cell surface marker that is a key component of the innate immune system. This monoclonal antibody is optimized for both mouse and human samples and is conjugated with FITC for easy detection in flow cytometry and immunofluorescence applications.CD11b, also known as integrin alpha M, is primarily expressed on the surface of myeloid cells such as monocytes, macrophages, and granulocytes, playing a crucial role in cell adhesion, migration, and phagocytosis.

Its involvement in the immune response makes it a valuable marker for studying inflammation, infection, and immune cell interactions.With its high specificity and versatility in detecting CD11b in various cell types, the Mouse/Human CD11b Monoclonal Antibody (FITC Conjugated) M1/70 (AGEL0306) is an essential tool for researchers exploring immunology, inflammation, and infectious diseases. It enables precise analysis and visualization of CD11b expression, providing valuable insights into the function and behavior of myeloid cells in both mouse and human samples.

Product Title:FITC Anti-Mouse/Human CD11b Antibody [M1/70]
SKU:AGEL0306
Size:50 Tests, 100 Tests, 200 Tests
Clone No:M1/70
Synonyms:Integrin alpha-M;Itgam;CD11 antigen-like family member B;CR-3 alpha chain;Leukocyte adhesion receptor MO1;CD11b;
Host Species:Rat
Reactivity:Human;Mouse
Application:FCM
Isotype:Rat IgG2b, κ
Isotype Control:FITC Rat IgG2b, κ Isotype Control[LTF-2]
Form:Liquid
Conjugation:FITC
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Swissprot:P05555 P11215
Gene ID:16409,3684
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD11b is a 170 kD glycoprotein also known as αM integrin, Mac-1 α subunit, Mol, CR3, and Ly-40. CD11b is a member of the integrin family, primarily expressed on granulocytes, monocytes/macrophages, dendritic cells, NK cells, and subsets of T and B cells. CD11b non-covalently associates with CD18 (β2 integrin) to form Mac-1. Mac-1 plays an important role in cell-cell interaction by binding its ligands ICAM-1 (CD54), ICAM-2 (CD102), ICAM-4 (CD242), iC3b, and fibrinogen.

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