Mouse Cyclophilin B Recombinant Protein (RPPB1537)
- SKU:
- RPPB1537
- Product Type:
- Recombinant Protein
- Species:
- Mouse
- Uniprot:
- P24369
- Research Area:
- Enzymes
Frequently bought together:
Description
| Product Name: | Mouse Cyclophilin B Recombinant Protein |
| Product Code: | RPPB1537 |
| Size: | 10µg |
| Species: | Mouse |
| Target: | Cyclophilin B |
| Synonyms: | Peptidyl-prolyl cis-trans isomerase B, PPIase B, CYP-S1, Cyclophilin B, Rotamase B, S-cyclophilin, SCYLP. |
| Source: | Escherichia Coli |
| Physical Appearance: | Sterile filtered colorless solution. |
| Formulation: | Cyclophilin B protein solution (1mg/ml) containing Phosphate Buffered Saline (pH7.4) and 10% glycerol. |
| Stability: | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles. |
| Purity: | Greater than 95.0% as determined by SDS-PAGE. |
| Amino Acid Sequence: | MGSSHHHHHH SSGLVPRGSH MGSMNDKKKG PKVTVKVYFD LQIGDESVGR VVFGLFGKTV PKTVDNFVAL ATGEKGFGYK NSKFHRVIKD FMIQGGDFTR GDGTGGKSIY GERFPDENFK LKHYGPGWVS MANAGKDTNG SQFFITTVKT SWLDGKHVVF GKVLEGMDVV RKVESTKTDSRDKPLKDVII VDSGKIEVEK PFAIAKE |
| Biological Activity: | Specific activity is > 1,000 nmol/min/mg, and is defined as the amount of enzyme that cleaves 1nmole of suc-AAFP-PNA per minute at 37C in Tris�HCl pH 8.0 using chymotrypsin. |
Cyclophilin B (also known as PPIB, peptidylpropyl isomerase B) is a cyclosporine-binding protein and is mainly located within the endoplasmic reticulum. It is associated with the secretory pathway and released in biological fluids. This protein can bind to cells derived from T- and B-lymphocytes, and may regulate cyclosporine A-mediated immunosuppression.
Cyclophilin B Mouse Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 207 amino acids (34-216 a.a) and having a molecular mass of 22.7kDa.Cyclophilin B is fused to a 24 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
| UniProt Protein Function: | PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. |
| UniProt Code: | P24369 |
| NCBI GenInfo Identifier: | 215273926 |
| NCBI Gene ID: | 19035 |
| NCBI Accession: | P24369.2 |
| UniProt Related Accession: | P24369 |
| Molecular Weight: | 23,713 Da |
| NCBI Full Name: | Peptidyl-prolyl cis-trans isomerase B |
| NCBI Synonym Full Names: | peptidylprolyl isomerase B |
| NCBI Official Symbol: | Ppib�� |
| NCBI Official Synonym Symbols: | Cphn2; Cphn-2; CyP-20b; AA408962; AA553318; AI844835�� |
| NCBI Protein Information: | peptidyl-prolyl cis-trans isomerase B |
| UniProt Protein Name: | Peptidyl-prolyl cis-trans isomerase B |
| UniProt Synonym Protein Names: | CYP-S1; Cyclophilin B; Rotamase B; S-cyclophilin; SCYLP |
| Protein Family: | Probable peptidyl-prolyl cis-trans isomerase |
| UniProt Gene Name: | Ppib�� |
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