The Mouse CD90.2 Monoclonal Antibody (PERCP-Cyanine5.5 Conjugated) is a valuable tool for researchers investigating CD90.2, a cell surface marker commonly used to identify and isolate specific cell populations. This antibody, clone 30-H12, is specifically designed for flow cytometry applications, allowing for accurate and reliable detection of CD90.2 expression in mouse samples.CD90.2, also known as Thy1.2, is a glycosylphosphatidylinositol-anchored protein involved in various cellular processes, including cell adhesion, migration, and signal transduction. It is widely used as a marker for stem cells, T cells, and certain subsets of leukocytes.
The precise detection of CD90.2 expression is crucial in studies related to stem cell research, immunology, and cancer biology.By utilizing this monoclonal antibody, researchers can confidently analyze and characterize CD90.2-expressing cells in their experiments. The PERCP-Cyanine5.5 conjugation provides excellent sensitivity and signal-to-noise ratio, allowing for accurate quantification and profiling of cells expressing CD90.2. This antibody is a valuable tool for understanding the role of CD90.2 in various biological processes and diseases, paving the way for advancements in regenerative medicine, immunotherapy, and cancer treatment.
PerCP/Cyanine5.5 Rat IgG2b, κ Isotype Control[LTF-2]
Form:
Liquid
Conjugation:
PerCP/Cyanine 5.5
Recommended Use:
Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/106 cells in 100 μL volume].
Spectrum:
Gene ID:
21838
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
CD90.2 is a 25-35 kD immunoglobulin superfamily member also known as Thy1.2. It is expressed on hematopoietic stem cells and neurons, all thymocytes, and peripheral T cells in Thy1.2 bearing mouse strains (Balb/c, CBA/J, C3H/He, C57BL/-, DBA, NZB/-). CD90.2 is a glycosylphosphatidylinositol (GPI)-anchored membrane glycoprotein involved in signal transduction. CD90.2 is involved in costimulation of lymphocyte proliferation and induction of hematopoietic stem cells differentiation. CD90.2 has been shown to interact with CD45. The 30H12 antibody has been reported to induce Ca2+ flux in thymocytes and, in combination with antibody against the CD3/TCR complex, promote thymocyte apoptosis and inhibit CD3-mediated proliferative responses of mature T lymphocytes.